Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL47743 | 1.00 | TSHR (0.34) | TSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL12398554 | 0.99 | TSHR (0.35) | TSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL2608074 | 0.94 | TSHR (0.34) | TSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL15355895 | 0.93 | ALDH1A1 (0.32) | TSHRALDH1A1CYP3A4 | |
| SCHEMBL14513850 | 0.93 | TSHR (0.37) | TSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL15355894 | 0.92 | TSHR (0.33) | TSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL12585804 | 0.90 | ALDH1A1 (0.30) | TSHRALDH1A1CYP3A4 | |
| SCHEMBL12891632 | 0.90 | ALDH1A1 (0.30) | TSHRALDH1A1CYP3A4 | |
| SCHEMBL13789040 | 0.89 | ALDH1A1 (0.31) | TSHRALDH1A1CYP3A4 | |
| SCHEMBL35484 | 0.88 | TSHR (0.36) | TSHRALDH1A1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140268028-A1 | SILICONE-CONTAINING CONTACT LENS HAVING CLAY TREATMENT APPLIED THERETO | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2014-09-18 | — | — | US | disclosed |