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SCHEMBL47743

SCHEMBL47743

C=COC(=O)OCCCC[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 2/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ CYP3A4 P08684 1/20 0.34
▸ HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16088296 1.00 TSHR (0.34) TSHRALDH1A1CYP3A4HPGD
SCHEMBL12398554 0.99 TSHR (0.35) TSHRALDH1A1CYP3A4HPGD
SCHEMBL2608074 0.94 TSHR (0.34) TSHRALDH1A1CYP3A4HPGD
SCHEMBL15355895 0.93 ALDH1A1 (0.32) TSHRALDH1A1CYP3A4
SCHEMBL14513850 0.93 TSHR (0.37) TSHRALDH1A1CYP3A4HPGD
SCHEMBL15355894 0.92 TSHR (0.33) TSHRALDH1A1CYP3A4HPGD
SCHEMBL12585804 0.90 ALDH1A1 (0.30) TSHRALDH1A1CYP3A4
SCHEMBL12891632 0.90 ALDH1A1 (0.30) TSHRALDH1A1CYP3A4
SCHEMBL13789040 0.89 ALDH1A1 (0.31) TSHRALDH1A1CYP3A4
SCHEMBL35484 0.88 TSHR (0.36) TSHRALDH1A1CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10036899-B2 Multi-piece insert device with glue seal for ophthalmic devices JOHNSON & JOHNSON VISION CARE, INC. (US) 2018-07-31 — — US disclosed
US-20180203254-A1 METHODS AND APPARATUS TO ENHANCE OXYGEN CONCENTRATIONS FOR ADVANCED OPHTHALMIC DEVICES JOHNSON & JOHNSON VISION CARE (US) 2018-07-19 — — US disclosed
US-20180203256-A1 METHODS AND APPARATUS TO ENHANCE OXYGEN CONCENTRATIONS FOR ADVANCED OPHTHALMIC DEVICES JOHNSON & JOHNSON VISION CARE (US) 2018-07-19 — — US disclosed
US-20180203255-A1 METHODS AND APPARATUS TO ENHANCE OXYGEN CONCENTRATIONS FOR ADVANCED OPHTHALMIC DEVICES JOHNSON & JOHNSON VISION CARE (US) 2018-07-19 — — US disclosed
US-20180203253-A1 METHODS AND APPARATUS TO ENHANCE OXYGEN CONCENTRATIONS FOR OPHTHALMIC DEVICES JOHNSON & JOHNSON VISION CARE (US) 2018-07-19 — — US disclosed
US-20180191035-A1 BIOMEDICAL ENERGIZATION ELEMENTS WITH POLYMER ELECTROLYTES AND CAVITY STRUCTURES JOHNSON & JOHNSON VISION CARE (US) 2018-07-05 — — US disclosed
US-20180173008-A1 METHODS AND APPARATUS FOR BIOMEDICAL DEVICES WITH CUSTOMIZED APPEARANCE JOHNSON & JOHNSON VISION CARE, INC. 2018-06-21 — — US disclosed
US-20180166665-A1 FLEXIBLE MICRO-BATTERY JOHNSON & JOHNSON VISION CARE (US) 2018-06-14 — — US disclosed
US-20180159091-A1 BIOCOMPATIBILITY OF BIOMEDICAL ENERGIZATION ELEMENTS JOHNSON & JOHNSON VISION CARE (US) 2018-06-07 — — US disclosed
US-9977260-B2 Sealing and encapsulation in energized ophthalmic devices with annular inserts JOHNSON & JOHNSON VISION CARE, INC. (US) 2018-05-22 — — US disclosed
US-20130085205-A1 SILICONE HYDROGELS HAVING IMPROVED CURING SPEED AND OTHER PROPERTIES JOHNSON & JOHNSON VISION CARE, INC. 2013-04-04 — — US disclosed
US-20120236254-A1 METHOD FOR USING A STACKED INTEGRATED COMPONENT MEDIA INSERT IN AN OPHTHALMIC DEVICE JOHNSON & JOHNSON VISION CARE, INC. 2012-09-20 — — US disclosed
US-20120234453-A1 STACKED INTEGRATED COMPONENT MEDIA INSERT FOR AN OPHTHALMIC DEVICE JOHNSON & JOHNSON VISION CARE, INC. 2012-09-20 — — US disclosed
US-20120212703-A1 POLYMERIC COMPOSITIONS COMPRISING AT LEAST ONE VOLUME EXCLUDING POLYMER JOHNSON & JOHNSON VISION CARE, INC. 2012-08-23 — — US disclosed
US-20120162600-A1 ENERGIZED OPHTHALMIC LENS INCLUDING STACKED INTEGRATED COMPONENTS JOHNSON & JOHNSON VISION CARE, INC. 2012-06-28 — — US disclosed
US-20120062834-A1 ENERGIZED BIOMEDICAL DEVICE JOHNSON & JOHNSON VISION CARE, INC. 2012-03-15 — — US disclosed
US-20110287118-A1 OPHTHALMIC LENS MOLD TREATMENT JOHNSON & JOHNSON VISION CARE, INC. 2011-11-24 — — US disclosed
US-20110275734-A1 NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND METHODS FOR MAKING AND USING THE SAME JOHNSON & JOHNSON VISION CARE, INC. 2011-11-10 — — US disclosed
US-20110157544-A1 OPHTHALMIC LENS MEDIA INSERT JOHNSON & JOHNSON VISION CARE, INC. 2011-06-30 — — US disclosed
US-7968650-B2 Polymeric compositions comprising at least one volume excluding polymer JOHNSON & JOHNSON VISION CARE, INC. (US) 2011-06-28 — — US disclosed