Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14513850 | 0.98 | TSHR (0.37) | TSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL15355894 | 0.97 | TSHR (0.33) | TSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL15355895 | 0.96 | ALDH1A1 (0.32) | TSHRALDH1A1CYP3A4 | |
| SCHEMBL12398554 | 0.96 | TSHR (0.35) | TSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL47743 | 0.94 | TSHR (0.34) | TSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL13789040 | 0.94 | ALDH1A1 (0.31) | TSHRALDH1A1CYP3A4 | |
| SCHEMBL16088296 | 0.94 | TSHR (0.34) | TSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL35484 | 0.94 | TSHR (0.36) | TSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL12891632 | 0.93 | ALDH1A1 (0.30) | TSHRALDH1A1CYP3A4 | |
| SCHEMBL12585804 | 0.93 | ALDH1A1 (0.30) | TSHRALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11971518-B2 | Shape engineering of particles to create a narrow spectral filter against a specific portion of the light spectrum | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2024-04-30 | — | — | US | disclosed |
| US-20240067622-A1 | PHOTOSTABLE MIMICS OF MACULAR PIGMENT | JOHNSON & JOHNSON VISION CARE (US) | 2024-02-29 | — | — | US | disclosed |
| US-20240067825-A1 | POLYMERIZABLE ABSORBERS OF UV AND HIGH ENERGY VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE (US) | 2024-02-29 | — | — | US | disclosed |
| US-11912800-B2 | Amide-functionalized polymerization initiators and their use in the manufacture of ophthalmic lenses | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2024-02-27 | — | — | US | disclosed |
| US-11829008-B2 | Increased stiffness center optic in soft contact lenses for astigmatism correction | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2023-11-28 | — | — | US | disclosed |
| US-11820899-B2 | Polymerizable absorbers of UV and high energy visible light | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2023-11-21 | — | — | US | disclosed |
| US-20230350099-A1 | SHAPE ENGINEERING OF PARTICLES TO CREATE A NARROW SPECTRAL FILTER AGAINST A SPECIFIC PORTION OF THE LIGHT SPECTRUM | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2023-11-02 | — | — | US | disclosed |
| US-11780953-B2 | Ophthalmic devices containing localized grafted networks and processes for their preparation and use | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2023-10-10 | — | — | US | disclosed |
| US-11754754-B2 | Silicone hydrogels comprising N-alkyl methacrylamides and contact lenses made thereof | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2023-09-12 | — | — | US | disclosed |
| US-11733440-B1 | Thermally stable nanoparticles and methods thereof | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2023-08-22 | — | — | US | disclosed |
| US-20070132120-A1 | Preferential release of an ophthalmic lens using a super-cooled fluid | BAUSCH & LOMB INCORPORATED | 2007-06-14 | — | — | US | disclosed |
| US-20070132119-A1 | Use of a super-cooled fluid in the manufacture of contact lenses | BAUSCH & LOMB INCORPORATED | 2007-06-14 | — | — | US | disclosed |
| US-20070132125-A1 | Use of a super-cooled fluid in lens processing | BAUSCH & LOMB INCORPORATED | 2007-06-14 | — | — | US | disclosed |
| US-20070132121-A1 | Method of cleaning molds using super-cooled fluids | BAUSCH & LOMB INCORPORATED | 2007-06-14 | — | — | US | disclosed |
| US-20070122540-A1 | Coatings on ophthalmic lenses | BAUSCH & LOMB INCORPORATED | 2007-05-31 | — | — | US | disclosed |
| US-20070120279-A1 | Method for coating lens material | BAUSCH & LOMB INCORPORATED | 2007-05-31 | — | — | US | disclosed |
| US-20070087113-A1 | Surface-modified medical devices and method of making | BAUSCH & LOMB INCORPORATED | 2007-04-19 | — | — | US | disclosed |
| US-20070048349-A1 | Surface-modified medical devices and methods of making | BAUSCH & LOMB INCORPORATED | 2007-03-01 | — | — | US | disclosed |
| US-20070049713-A1 | Polymeric materials having enhanced ion and water transport property and medical devices comprising same | BAUSCH & LOMB INCORPORATED | 2007-03-01 | — | — | US | disclosed |
| US-20070035693-A1 | Contact lenses and methods for reducing conjunctival pressure in contact lens wearers | COOPERVISION INC. (US) | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240067622-A1 | PHOTOSTABLE MIMICS OF MACULAR PIGMENT | CRY1, PDE6C, PDE6A | TSHR 2804/4885ALDH1A1 2396/4885CYP3A4 618/4885 |
| US-11912800-B2 | Amide-functionalized polymerization initiators and their use in the manufacture of ophthalmic lenses | CRYAA, UACA, CRYAB | TSHR 1161/4885ALDH1A1 1469/4885CYP3A4 2005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.