SCHEMBL35484

SCHEMBL35484

C=COC(=O)OCCCC[Si](C)(C)O[Si](C)(C)CCCCOC(=O)OC=C

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP3A4 P08684 1/20 0.36
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15355903 0.98 TSHR (0.39) TSHRALDH1A1CYP3A4HPGD
SCHEMBL15355898 0.98 TSHR (0.35) TSHRALDH1A1CYP3A4HPGD
SCHEMBL8767122 0.94 ACHE (0.35) TSHRALDH1A1CYP3A4HPGD
SCHEMBL15355894 0.94 TSHR (0.33) TSHRALDH1A1CYP3A4HPGD
SCHEMBL2608074 0.94 TSHR (0.34) TSHRALDH1A1CYP3A4HPGD
SCHEMBL15355895 0.93 ALDH1A1 (0.32) TSHRALDH1A1CYP3A4
SCHEMBL14513850 0.92 TSHR (0.37) TSHRALDH1A1CYP3A4HPGD
SCHEMBL16775599 0.91 TSHR (0.35) TSHRALDH1A1CYP3A4
SCHEMBL12398554 0.90 TSHR (0.35) TSHRALDH1A1CYP3A4HPGD
SCHEMBL13330235 0.89 TSHR (0.35) TSHRALDH1A1CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 681 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118994496-A Contact lens and silicone contact lens 望隼科技股份有限公司 2024-11-22 CN claimed
US-20240384089-A1 CONTACT LENS AND SILICONE HYDROGEL CONTACT LENS VIZIONFOCUS INC. (TW) 2024-11-21 US claimed
EP-0757033-B1 Vinyl carbonate and vinyl carbamate monomers for a contact lens material BAUSCH & LOMB (US) 1999-03-03 EP claimed
EP-0396364-B1 Copolymers of vinyl carbonate and vinyl carbamate as contact lens material BAUSCH & LOMB (US) 1997-06-11 EP claimed
EP-0396364-A2 Novel vinyl carbonate and vinyl carbamate contact lens material monomers BAUSCH & LOMB INCORPORATED (US) 1990-11-07 EP claimed
US-12638613-B2 Ophthalmic lenses and their manufacture by in-mold modification JOHNSON & JOHNSON VISION CARE, INC. (US) 2026-05-26 US disclosed
US-12624214-B2 Polymerizable absorbers of UV and high energy visible light JOHNSON & JOHNSON VISION CARE, INC. (US) 2026-05-12 US disclosed
EP-4408852-B1 ANTHRAQUINONE-FUNCTIONALIZED POLYMERIZATION INITIATORS AND THEIR USE IN THE MANUFACTURE OF OPHTHALMIC LENSES JOHNSON & JOHNSON VISION CARE (US) 2026-04-08 EP disclosed
US-12595370-B2 Polymerizable absorbers of UV and high energy visible light JOHNSON & JOHNSON VISION CARE, INC. (US) 2026-04-07 US disclosed
US-12595371-B2 Contact lens with improved vision break-up time JOHNSON & JOHNSON VISION CARE, INC. (US) 2026-04-07 US disclosed
US-20260070882-A1 PHOTOSTABLE MIMICS OF MACULAR PIGMENT JOHNSON & JOHNSON VISION CARE (US) 2026-03-12 US disclosed
EP-4707342-A2 CONTACT LENS DISPLAYING IMPROVED VISION ATTRIBUTES Johnson & Johnson Vision Care, Inc. (US) 2026-03-11 EP disclosed
EP-0559784-A1 SURFACE-ACTIVE MACROMONOMERS. BAUSCH & LOMB (US) 1993-09-15 EP disclosed
US-5219965-A Adding polymerizable surfactant to monomer mixture; contact lenses BAUSCH & LOMB INCORPORATED (US) 1993-06-15 US disclosed
US-5177165-A Contact lenses BAUSCH & LOMB INCORPORATED (US) 1993-01-05 US disclosed
US-5158717-A Contact lenses from copolymerizing silicone and hydrophilic monomers in mold produced from an acrylonitrile copolymer resin; melt processability, wettability BAUSCH & LOMB INCORPORATED (US) 1992-10-27 US disclosed
US-5135297-A Immersing a contact lens in an aqueous dispersion of a polymerizable surfactant macromer, a crosslinker and a free radical catalyst and irradiating with UV light; wetting agents BAUSCH & LOMB INCORPORATED (US) 1992-08-04 US disclosed
WO-1992009639-A2 SURFACE-ACTIVE MACROMONOMERS BAUSCH & LOMB INCORPORATED (US) 1992-06-11 WO disclosed
US-5070215-A Gas permeable contact lenses BAUSCH & LOMB INCORPORATED (US) 1991-12-03 US disclosed
EP-0396364-A2 Novel vinyl carbonate and vinyl carbamate contact lens material monomers BAUSCH & LOMB INCORPORATED (US) 1990-11-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12595370-B2 Polymerizable absorbers of UV and high energy visible light NLRP3, NLRP1, XDH TSHR 980/4885ALDH1A1 738/4885CYP3A4 19/4885
US-12595371-B2 Contact lens with improved vision break-up time CUTA, VEGFA, CASP14 TSHR 3672/4885ALDH1A1 3458/4885CYP3A4 325/4885
US-12638613-B2 Ophthalmic lenses and their manufacture by in-mold modification UACA, AXL, CRYZ TSHR 2482/4885ALDH1A1 1768/4885CYP3A4 1323/4885
US-12624214-B2 Polymerizable absorbers of UV and high energy visible light CRY1, SCNN1G, MALT1 TSHR 832/4885ALDH1A1 1349/4885CYP3A4 679/4885
US-20260070882-A1 PHOTOSTABLE MIMICS OF MACULAR PIGMENT CRY1, CRY2, XPA TSHR 3190/4885ALDH1A1 3685/4885CYP3A4 1582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.