Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.69 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.69 |
| ▸ | OXER1 | Q8TDS5 | 4/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | PPARG | P37231 | 4/20 | 0.69 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.69 |
| ▸ | RXRA | P19793 | 2/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.68 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.68 |
| ▸ | RELA | Q04206 | 1/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.56 |
| ▸ | F7 | P08709 | 3/20 | 0.56 |
| ▸ | F3 | P13726 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | PPARD | Q03181 | 2/20 | 0.56 |
| ▸ | PPARA | Q07869 | 2/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18258510 | 1.00 | ALDH1A1 (0.69) | ALDH1A1CYP19A1OXER1MAPTPPARG | |
| SCHEMBL16681498 | 0.90 | NFKB1 (0.80) | ALDH1A1CYP19A1OXER1MAPTPPARG | |
| SCHEMBL18258565 | 0.90 | NFKB1 (0.80) | ALDH1A1CYP19A1OXER1MAPTPPARG | |
| SCHEMBL1141473 | 0.89 | NFKB1 (0.56) | ALDH1A1CYP19A1OXER1MAPTPPARG | |
| SCHEMBL18258559 | 0.88 | NFKB1 (0.78) | ALDH1A1CYP19A1OXER1MAPTPPARG | |
| SCHEMBL18258562 | 0.88 | NFKB1 (0.78) | ALDH1A1CYP19A1OXER1MAPTPPARG | |
| SCHEMBL23646056 | 0.85 | ALDH1A1 (0.76) | ALDH1A1CYP19A1OXER1MAPTPPARG | |
| SCHEMBL23646062 | 0.85 | ALDH1A1 (0.76) | ALDH1A1CYP19A1OXER1MAPTPPARG | |
| SCHEMBL23646058 | 0.85 | ALDH1A1 (0.76) | ALDH1A1CYP19A1OXER1MAPTPPARG | |
| SCHEMBL23646060 | 0.85 | ALDH1A1 (0.76) | ALDH1A1CYP19A1OXER1MAPTPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9315447-B2 | Compositions and methods for the treatment of inflammation | A.T. Resolve Sarl (CH) | 2016-04-19 | — | — | US | disclosed |
| US-20140275247-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATION | A.T. Resolve Sarl (CH) | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275247-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATION | ALOX15B, ALOX5, ALOX12 | ALDH1A1 2449/4885CYP19A1 772/4885OXER1 273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.