SCHEMBL1609280

SCHEMBL1609280

COc1cc2nc(C)sc2cc1OC

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.70
ATM Q13315 1/20 0.70
MAPT P10636 4/20 0.63
RAB9A P51151 4/20 0.63
SMN1; SMN2 Q16637 3/20 0.63
NPC1 O15118 3/20 0.63
HSD17B10 Q99714 2/20 0.63
ALDH1A1 P00352 2/20 0.63
TP53 P04637 1/20 0.63
PKM P14618 1/20 0.63
HPGD P15428 1/20 0.63
GAA P10253 1/20 0.59
STING1 Q86WV6 1/20 0.49
POLB P06746 1/20 0.48
TSHR P16473 1/20 0.47
LMNA P02545 3/20 0.45
NQO2 P16083 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CHRNB2 P17787 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30423168 1.00 ALOX15 (0.70) ALOX15ATMMAPTRAB9ASMN1; SMN2
SCHEMBL9310828 0.89 GAA (0.66) ALOX15ATMMAPTRAB9ASMN1; SMN2
SCHEMBL18618286 0.89 ALOX15 (0.66) ALOX15ATMMAPTRAB9ASMN1; SMN2
SCHEMBL18201941 0.86 ALOX15 (0.55) ALOX15ATMMAPTRAB9ASMN1; SMN2
SCHEMBL18587907 0.85 ALOX15 (0.62) ALOX15ATMMAPTRAB9ASMN1; SMN2
SCHEMBL15839256 0.85 ALOX15 (0.58) ALOX15ATMMAPTRAB9ASMN1; SMN2
SCHEMBL14970154 0.85 ALOX15 (0.62) ALOX15ATMMAPTRAB9ASMN1; SMN2
SCHEMBL16787513 0.85 ALOX15 (0.62) ALOX15ATMMAPTRAB9ASMN1; SMN2
SCHEMBL9434842 0.85 ALOX15 (0.58) ALOX15ATMMAPTRAB9ASMN1; SMN2
SCHEMBL1914041 0.85 ALOX15 (0.62) ALOX15ATMMAPTRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118355041-A Method for underwater bonding 汉高股份有限及两合公司 2024-07-16 CN claimed
EP-3464446-B1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM Henkel IP & Holding GmbH (DE) 2021-06-23 EP claimed
CN-109476874-B Two-part cyanoacrylate curable adhesive systems 汉高知识产权控股有限责任公司 2021-04-16 CN claimed
EP-3464446-A1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM Henkel IP & Holding GmbH (DE) 2019-04-10 EP claimed
CN-109476874-A Bi-component cyanoacrylate curable adhesive system 汉高知识产权控股有限责任公司 2019-03-15 CN claimed
US-10100235-B2 Two-part cyanoacrylate curable adhesive system Henkel IP & Holding GmbH (DE) 2018-10-16 US claimed
WO-2017202698-A1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM Henkel IP & Holding GmbH (DE) 2017-11-30 WO claimed
US-20170335151-A1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM HENKEL AG & CO. KGAA (DE) 2017-11-23 US claimed
EP-2346956-A1 ACTIVATORS FOR TWO PART CYANOACRYLATE ADHESIVES Loctite (R & D) Limited (IE) 2011-07-27 EP claimed
WO-2010046412-A1 ACTIVATORS FOR TWO PART CYANOACRYLATE ADHESIVES LOCTITE (R & D) LIMITED (IE) 2010-04-29 WO claimed
EP-1087952-B1 BENZAZOLE COMPOUNDS AND THEIR USE NOVARTIS AG (CH) 2004-06-02 EP claimed
US-6410578-B1 INSECTICIDE, MITICIES, PESTICIDE NOVARTIS ANIMAL HEALTH US, INC. 2002-06-25 US claimed
EP-1087952-A1 BENZAZOLE COMPOUNDS AND THEIR USE Novartis AG (CH) 2001-04-04 EP claimed
WO-1999065886-A1 BENZAZOLE COMPOUNDS AND THEIR USE NOVARTIS AG (CH) 1999-12-23 WO claimed
US-20240318052-A1 METHOD OF UNDERWATER BONDING HENKEL AG & CO KGAA (DE) 2024-09-26 US disclosed
US-11815448-B2 Method, reagent, and chip for measuring analyte concentration in specimen TERUMO KABUSHIKI KAISHA (JP) 2023-11-14 US disclosed
US-11739083-B2 Disposable sensor chip with reagent including 2-substituted benzothiazolyl-3-substituted phenyl-5-substituted sulfonated phenyl-2H-tetrazolium salt TERUMO KABUSHIKI KAISHA (JP) 2023-08-29 US disclosed
WO-1999065886-A1 BENZAZOLE COMPOUNDS AND THEIR USE NOVARTIS AG (CH) 1999-12-23 WO disclosed
WO-1998000756-A1 SILVER HALIDE EMULSIONS POLAROID CORPORATION (US) 1998-01-08 WO disclosed
US-5601963-A SILVER GRAINS HAVE BEEN SPECTRALLY SENSITIZED TO NEAR INFRARED RADIATION AT WAVELENGTHS ABOVE 700 NM WITH A PARTICULAR CLASS OF CYANINE DYES POLAROID CORPORATION (US) 1997-02-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11815448-B2 Method, reagent, and chip for measuring analyte concentration in specimen STUB1, MPO, ALDH1A2 ALOX15 1578/4885ATM 3923/4885MAPT 3928/4885
US-11739083-B2 Disposable sensor chip with reagent including 2-substituted benzothiazolyl-3-substituted phenyl-5-substituted sulfonated phenyl-2H-tetrazolium salt STUB1, BTK, TST ALOX15 3458/4885ATM 1875/4885MAPT 1351/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.