Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 6/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.38 |
| ▸ | PSD | A5PKW4 | 3/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.35 |
| ▸ | GCGR | P47871 | 2/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16094741 | 0.90 | MAPK14 (0.48) | MAPK14GSK3AGSK3BKDM1AMAPK13 | |
| SCHEMBL16095505 | 0.80 | KDM4C (0.56) | MAPK14GSK3BKDM4C | |
| SCHEMBL16094449 | 0.80 | USP30 (0.36) | MAPK14IDO1KDM1A | |
| SCHEMBL16095177 | 0.80 | KDM4C (0.39) | MAPK14GSK3BIDH1KDM4CMAPK13 | |
| SCHEMBL16095315 | 0.78 | KDM4C (0.60) | KDM4C | |
| SCHEMBL16095224 | 0.72 | MAPK14 (0.48) | MAPK14GSK3AGSK3BMAPK13GCGR | |
| SCHEMBL16095914 | 0.72 | MAPK14 (0.50) | MAPK14GSK3AGSK3BKDM4CMAPK13 | |
| SCHEMBL16095105 | 0.72 | MAPK14 (0.46) | MAPK14GSK3AGSK3BKDM4CMAPK13 | |
| SCHEMBL16095484 | 0.72 | USP30 (0.38) | — | |
| SCHEMBL16033590 | 0.72 | KDM4C (0.67) | MAPK14KDM4CKDM1AMAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |