Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.64 |
| ▸ | MMP9 | P14780 | 2/20 | 0.64 |
| ▸ | MMP8 | P22894 | 2/20 | 0.64 |
| ▸ | MMP13 | P45452 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | TNKS | O95271 | 2/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12713529 | 0.85 | MMP2 (0.64) | MMP2MMP9MMP8MMP13KMT2A | |
| SCHEMBL14664339 | 0.81 | MMP2 (0.60) | MMP2MMP9MMP8MMP13NPC1 | |
| SCHEMBL14664340 | 0.81 | MMP2 (0.57) | MMP2MMP9MMP8MMP13KMT2A | |
| SCHEMBL10694677 | 0.79 | MMP2 (1.00) | MMP2MMP9MMP8MMP13KMT2A | |
| SCHEMBL10689470 | 0.73 | MMP2 (0.70) | MMP2MMP9MMP8MMP13KMT2A | |
| SCHEMBL14664344 | 0.72 | CYP2A6 (0.41) | MMP2MMP9MMP8KMT2ANPC1 | |
| SCHEMBL10690246 | 0.69 | MMP2 (0.68) | MMP2MMP9MMP8MMP13KMT2A | |
| SCHEMBL30360160 | 0.69 | MMP2 (0.68) | MMP2MMP9MMP8MMP13KMT2A | |
| SCHEMBL10688373 | 0.69 | MMP2 (0.68) | MMP2MMP9MMP8MMP13KMT2A | |
| SCHEMBL10691037 | 0.69 | MMP2 (0.68) | MMP2MMP9MMP8MMP13KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086817-A1 | ANTI-BACTERIAL AGENTS FROM BENZO[D]HETEROCYCLIC SCAFFOLDS FOR PREVENTION AND TREATMENT OF MULTIDRUG RESISTANT BACTERIA | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2011-04-14 | — | — | US | claimed |
| WO-2009158118-A2 | ANTI-BACTERIAL AGENTS FROM BENZO[D]HETEROCYCLIC SCAFFOLDS FOR PREVENTION AND TREATMENT OF MULTIDRUG RESISTANT BACTERIA | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2009-12-30 | — | — | WO | claimed |
| US-9617249-B2 | Benzoheterocyclic anti-bacterial agents | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2017-04-11 | — | — | US | disclosed |
| US-9617249-B2 | Benzoheterocyclic anti-bacterial agents | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2017-04-11 | — | — | US | disclosed |
| US-20130143841-A1 | BENZOHETEROCYCLIC ANTI-BACTERIAL AGENTS | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2013-06-06 | — | — | US | disclosed |
| US-20130143841-A1 | BENZOHETEROCYCLIC ANTI-BACTERIAL AGENTS | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2013-06-06 | — | — | US | disclosed |
| US-8362268-B2 | Anti-bacterial agents from benzo[d]heterocyclic scaffolds for prevention and treatment of multidrug resistant bacteria | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2013-01-29 | — | — | US | disclosed |
| US-8362268-B2 | Anti-bacterial agents from benzo[d]heterocyclic scaffolds for prevention and treatment of multidrug resistant bacteria | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2013-01-29 | — | — | US | disclosed |
| US-20110086817-A1 | ANTI-BACTERIAL AGENTS FROM BENZO[D]HETEROCYCLIC SCAFFOLDS FOR PREVENTION AND TREATMENT OF MULTIDRUG RESISTANT BACTERIA | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2011-04-14 | — | — | US | disclosed |
| WO-2009158118-A2 | ANTI-BACTERIAL AGENTS FROM BENZO[D]HETEROCYCLIC SCAFFOLDS FOR PREVENTION AND TREATMENT OF MULTIDRUG RESISTANT BACTERIA | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2009-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086817-A1 | ANTI-BACTERIAL AGENTS FROM BENZO[D]HETEROCYCLIC SCAFFOLDS FOR PREVENTION AND TREATMENT OF MULTIDRUG RESISTANT BACTERIA | SBDS, PYCARD, AAAS | MMP2 1149/4885MMP9 893/4885MMP8 451/4885 |
| US-20130143841-A1 | BENZOHETEROCYCLIC ANTI-BACTERIAL AGENTS | MRPL21, BCOR, BCR | MMP2 1193/4885MMP9 1138/4885MMP8 322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.