Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL75687 | 0.74 | SLC9A1 (0.43) | SLC9A1ATMMAPK1POLBKEAP1 | |
| SCHEMBL655742 | 0.74 | POLB (0.48) | SLC9A1ATMMAPK1POLBKEAP1 | |
| SCHEMBL4737092 | 0.71 | SLC9A1 (0.34) | SLC9A1ATMMAPK1POLBKEAP1 | |
| SCHEMBL1264258 | 0.70 | MAPT (0.43) | SLC9A1ATMMAPK1POLBKEAP1 | |
| SCHEMBL811367 | 0.70 | ATM (0.39) | SLC9A1ATMMAPK1POLBKEAP1 | |
| SCHEMBL558259 | 0.70 | ATM (0.39) | SLC9A1ATMMAPK1POLBKEAP1 | |
| SCHEMBL407498 | 0.70 | POLB (0.39) | SLC9A1ATMMAPK1POLBKEAP1 | |
| SCHEMBL2073661 | 0.70 | POLB (0.39) | SLC9A1ATMMAPK1POLBKEAP1 | |
| SCHEMBL1381878 | 0.69 | SLC9A1 (0.44) | SLC9A1ATMMAPK1POLBKEAP1 | |
| SCHEMBL1831523 | 0.69 | ALDH1A1 (0.42) | ATMMAPK1POLBSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | Bridgestone Corporation (JP) | 2016-01-20 | — | — | EP | claimed |
| WO-2014149931-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORPORATION (JP) | 2014-09-25 | — | — | WO | claimed |