Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16097481 | 0.74 | SLC9A1 (0.36) | POLBMAPK1ATMMAPTALDH1A1 | |
| SCHEMBL2073661 | 0.73 | POLB (0.39) | POLBMAPK1ATMMAPTALDH1A1 | |
| SCHEMBL1264258 | 0.73 | MAPT (0.43) | POLBMAPK1ATMMAPTALDH1A1 | |
| SCHEMBL811367 | 0.73 | ATM (0.39) | POLBMAPK1ATMDGAT1MAPT | |
| SCHEMBL75687 | 0.73 | SLC9A1 (0.43) | POLBMAPK1ATMMAPTALDH1A1 | |
| SCHEMBL407498 | 0.73 | POLB (0.39) | POLBMAPK1ATMDGAT1MAPT | |
| SCHEMBL558259 | 0.73 | ATM (0.39) | POLBMAPK1ATMDGAT1MAPT | |
| SCHEMBL1491295 | 0.72 | ENPP2 (0.41) | ALDH1A1CYP3A4KDM4EMEN1KMT2A | |
| SCHEMBL1491376 | 0.72 | ENPP2 (0.41) | ALDH1A1KEAP1KDM4EMEN1KMT2A | |
| SCHEMBL2103982 | 0.72 | POLB (0.39) | POLBMAPK1ATMDGAT1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110713588-B | Hardmask composition, hardmask layer and method of forming pattern | 三星SDI株式会社 | 2022-08-09 | — | — | CN | claimed |
| US-11214678-B2 | Hardmask composition, hardmask layer and method of forming patterns | SAMSUNG SDI CO., LTD. (KR) | 2022-01-04 | — | — | US | claimed |
| CN-110713588-A | Hardmask composition, hardmask layer and method of forming pattern | 三星SDI株式会社 | 2020-01-21 | — | — | CN | claimed |
| US-10472360-B2 | Purine diones as Wnt pathway modulators | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2019-11-12 | — | — | US | claimed |
| US-20170334912-A1 | Purine Diones As Wnt Pathway Modulators | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2017-11-23 | — | — | US | claimed |
| EP-2428577-B1 | Preparation of tyrosinase-inhibiting hydroxybenzyl and hydroxypyranonemethyl esters | EASTMAN CHEM CO (US) | 2014-01-22 | — | — | EP | claimed |
| WO-2010043711-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | UNIVERSITAET DES SAARLANDES (DE) | 2010-04-22 | — | — | WO | claimed |
| EP-2177510-A1 | Allosteric protein kinase modulators | Universität des Saarlandes (DE) | 2010-04-21 | — | — | EP | claimed |
| CN-110713588-B | Hardmask composition, hardmask layer and method of forming pattern | 三星SDI株式会社 | 2022-08-09 | — | — | CN | disclosed |
| US-11214678-B2 | Hardmask composition, hardmask layer and method of forming patterns | SAMSUNG SDI CO., LTD. (KR) | 2022-01-04 | — | — | US | disclosed |
| CN-110713588-A | Hardmask composition, hardmask layer and method of forming pattern | 三星SDI株式会社 | 2020-01-21 | — | — | CN | disclosed |
| CN-104529906-A | Method for improving water solubility of hydroxybenzimidazolyl compound | TIANJIN INST PHARM RESEARCH | 2015-04-22 | — | — | CN | disclosed |
| CN-104529906-A | Method for improving water solubility of hydroxybenzimidazolyl compound | TIANJIN INST PHARM RESEARCH | 2015-04-22 | — | — | CN | disclosed |
| US-8912186-B2 | Allosteric protein kinase modulators | UNIVERSITAET DES SAARLANDES (DE) | 2014-12-16 | — | — | US | disclosed |
| US-7935706-B2 | Nitrogen-containing heterocycle derivatives substituted with cyclic group | SHIONOGI & CO., LTD. (JP) | 2011-05-03 | — | — | US | disclosed |
| WO-2011029832-A1 | NOVEL THIAZOL AND OXAZOL HEPCIDINE ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2011-03-17 | — | — | WO | disclosed |
| WO-2010043711-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | UNIVERSITAET DES SAARLANDES (DE) | 2010-04-22 | — | — | WO | disclosed |
| EP-2177510-A1 | Allosteric protein kinase modulators | Universität des Saarlandes (DE) | 2010-04-21 | — | — | EP | disclosed |
| US-20090062261-A1 | NITROGEN-CONTAINING HETEROCYCLE DERIVATIVES SUBSTITUTED WITH CYCLIC GROUP | SHIONOGI & CO., LTD. (JP) | 2009-03-05 | — | — | US | disclosed |
| EP-1988077-A1 | NIROGENOUS HETEROCYCLIC DERIVATIVES SUBSTITUTED WITH CYCLIC GROUPS | SHIONOGI & CO., LTD. (JP) | 2008-11-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170334912-A1 | Purine Diones As Wnt Pathway Modulators | WNT1, WNT3A, CTNNB1 | POLB 1739/4885MAPK1 920/4885ATM 1515/4885 |
| US-10472360-B2 | Purine diones as Wnt pathway modulators | WNT1, WNT3A, CTNNB1 | POLB 1739/4885MAPK1 920/4885ATM 1515/4885 |
| US-20090062261-A1 | NITROGEN-CONTAINING HETEROCYCLE DERIVATIVES SUBSTITUTED WITH CYCLIC GROUP | NR4A1, NR0B2, NR0B1 | POLB 3861/4885MAPK1 1586/4885ATM 4021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.