Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 5/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL558259 | 0.73 | ATM (0.39) | POLBATMMAPK1MAPTALDH1A1 | |
| SCHEMBL655742 | 0.73 | POLB (0.48) | POLBATMMAPK1MAPTALDH1A1 | |
| SCHEMBL1264258 | 0.73 | MAPT (0.43) | POLBATMMAPK1MAPTALDH1A1 | |
| SCHEMBL2073661 | 0.73 | POLB (0.39) | POLBATMMAPK1MAPTALDH1A1 | |
| SCHEMBL75687 | 0.73 | SLC9A1 (0.43) | POLBATMMAPK1MAPTALDH1A1 | |
| SCHEMBL811367 | 0.73 | ATM (0.39) | POLBATMMAPK1MAPTALDH1A1 | |
| SCHEMBL4737092 | 0.70 | SLC9A1 (0.34) | POLBATMMAPK1MAPTALDH1A1 | |
| SCHEMBL67806 | 0.70 | HTT (0.42) | POLBATMMAPK1MAPTALDH1A1 | |
| SCHEMBL16097481 | 0.70 | SLC9A1 (0.36) | POLBATMMAPK1MAPTALDH1A1 | |
| SCHEMBL11625717 | 0.69 | POLB (0.50) | POLBMAPTALDH1A1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392722-A4 | ECHINOCANDIN PROCESS | MERCK & CO INC (US) | 2007-04-18 | — | — | EP | claimed |
| US-20040158034-A1 | Echinocandin process | MERCK SHARP & DOHME CORP. | 2004-08-12 | — | — | US | claimed |
| EP-1392722-A2 | ECHINOCANDIN PROCESS | Merck & Co., Inc. (US) | 2004-03-03 | — | — | EP | claimed |
| WO-2002083713-A2 | ECHINOCANDIN PROCESS | MERCK & CO., INC. (US) | 2002-10-24 | — | — | WO | claimed |
| CN-109311197-B | Polyamide resin composite molded article and method for producing same | 东丽株式会社 | 2020-11-27 | — | — | CN | disclosed |
| US-8361627-B2 | Anti-corrosion layer for aluminum and magnesium alloys | EADS DEUTSCHLAND GMBH (DE) | 2013-01-29 | — | — | US | disclosed |
| US-20120021232-A1 | ANTI-CORROSION LAYER FOR ALUMINUM AND MAGNESIUM ALLOYS | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2012-01-26 | — | — | US | disclosed |
| EP-2379623-A1 | ANTI-CORROSION LAYER FOR ALUMINUM AND MAGNESIUM ALLOYS | EADS Deutschland GmbH (DE) | 2011-10-26 | — | — | EP | disclosed |
| WO-2010081757-A1 | ANTI-CORROSION LAYER FOR ALUMINUM AND MAGNESIUM ALLOYS | EADS DEUTSCHLAND GMBH (DE) | 2010-07-22 | — | — | WO | disclosed |
| US-4873346-A | BRONCHODILATORS, TREATMENT OF ASTHMA | THE UPJOHN COMPANY (US) | 1989-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040158034-A1 | Echinocandin process | EML4, BTD, NAT1 | POLB 3017/4885ATM 2079/4885MAPK1 4332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.