Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | WEE1 | P30291 | 1/20 | 0.36 |
| ▸ | RORA | P35398 | 1/20 | 0.36 |
| ▸ | RORB | Q92753 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16104960 | 0.85 | PTGER4 (0.57) | ALDH1A1HPGDPTGER4CNR2RORC | |
| SCHEMBL16093825 | 0.83 | PGR (0.41) | ALDH1A1HPGDPTGER4CNR2RORC | |
| SCHEMBL16093698 | 0.81 | ALDH1A1 (0.58) | ALDH1A1HPGDPTGER4CNR2KDM4E | |
| SCHEMBL16093752 | 0.80 | HPGD (0.44) | ALDH1A1HPGDCNR2KDM4ELMNA | |
| SCHEMBL16099112 | 0.79 | HPGD (0.55) | ALDH1A1HPGDCNR2KDM4ELMNA | |
| SCHEMBL16099561 | 0.75 | KDM4E (0.47) | ALDH1A1HPGDCNR2KDM4ELMNA | |
| SCHEMBL16097572 | 0.75 | ALDH1A1 (0.44) | ALDH1A1HPGDKDM4ELMNARORC | |
| SCHEMBL16099757 | 0.73 | PTGER4 (0.54) | ALDH1A1HPGDPTGER4CNR2KDM4E | |
| SCHEMBL16093634 | 0.71 | MAPT (0.53) | CNR2LMNAPOLBMAPT | |
| SCHEMBL625395 | 0.70 | HPGD (0.51) | ALDH1A1HPGDCNR2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014153043-A1 | COMPOUNDS AND METHODS FOR TREATING CANCERS | HEALTH RESEARCH, INC. (US) | 2014-09-25 | — | — | WO | disclosed |