Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11734144 | 0.80 | TDP1 (0.41) | LMNAALDH1A1MAPTTDP1MEN1 | |
| Sulfuric Acid SCHEMBL11734578 | 0.75 | LMNA (0.40) | POLBLMNAALDH1A1MAPTTDP1 | |
| SCHEMBL29865871 | 0.73 | PDE10A (0.41) | PDE10ACYP1A2CYP2C9CYP2C19POLB | |
| SCHEMBL5077937 | 0.72 | MAPT (0.45) | PDE10ACYP1A2CYP2C9CYP2C19POLB | |
| SCHEMBL5074722 | 0.72 | ALDH1A1 (0.40) | PDE10ACYP1A2CYP2C9CYP2C19POLB | |
| SCHEMBL29866672 | 0.69 | PDE10A (0.40) | PDE10ACYP1A2CYP2C9CYP2C19POLB | |
| SCHEMBL6512953 | 0.68 | PDE10A (0.60) | PDE10ACYP1A2CYP2C9CYP2C19POLB | |
| SCHEMBL29940575 | 0.68 | PDE10A (0.60) | PDE10ACYP1A2CYP2C9CYP2C19POLB | |
| SCHEMBL16098130 | 0.68 | GAA (0.67) | PDE10APOLBNPC1RAB9ALMNA | |
| SCHEMBL1736405 | 0.66 | ALDH1A1 (0.57) | PDE10APOLBNPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014153055-A2 | COMPOUNDS AND METHODS FOR TREATING CANCERS | HEALTH RESEARCH, INC. (US) | 2014-09-25 | — | — | WO | disclosed |