Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | PLAU | P00749 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5294872 | 0.82 | AKR1C3 (0.41) | ALDH1A1ALOX15AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL16098563 | 0.80 | AKR1C3 (0.56) | ALOX15AKR1C3AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL16122066 | 0.79 | ALDH1A1 (0.46) | ALDH1A1ALOX15AKR1C2AKR1C1CES2 | |
| SCHEMBL29063660 | 0.79 | ERN1 (0.42) | ALDH1A1AKR1C2AKR1C1LMNAKMT2A | |
| SCHEMBL16098934 | 0.78 | DGAT1 (0.55) | ALDH1A1ALOX15AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL181200 | 0.78 | ALDH1A1 (0.52) | ALDH1A1ALOX15AKR1C2AKR1C1DGAT1 | |
| SCHEMBL29401981 | 0.78 | ALDH1A1 (0.52) | ALDH1A1ALOX15AKR1C2AKR1C1DGAT1 | |
| SCHEMBL2301770 | 0.77 | ALDH1A1 (0.44) | ALDH1A1ALOX15CES2CES1 | |
| SCHEMBL7682107 | 0.76 | AKR1C3 (0.47) | ALDH1A1ALOX15AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL16122567 | 0.75 | ALDH1A1 (0.43) | ALDH1A1ALOX15CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111718281-A | Synthetic structural unit for preparing material for organic electroluminescent device | 默克专利有限公司 | 2020-09-29 | — | — | CN | disclosed |
| EP-2976322-B1 | SYNTHETIC BUILDING BLOCKS FOR THE PRODUCTION OF MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2019-11-20 | — | — | EP | disclosed |
| EP-2976322-B1 | SYNTHETIC BUILDING BLOCKS FOR THE PRODUCTION OF MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2019-11-20 | — | — | EP | disclosed |
| US-10407384-B2 | Synthetic building blocks for the production of materials for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2019-09-10 | — | — | US | disclosed |
| US-10407384-B2 | Synthetic building blocks for the production of materials for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2019-09-10 | — | — | US | disclosed |
| US-20170313650-A1 | SYNTHETIC BUILDING BLOCKS FOR THE PRODUCTION OF MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | UDC IRELAND LIMITED (IE) | 2017-11-02 | — | — | US | disclosed |
| US-20170313650-A1 | SYNTHETIC BUILDING BLOCKS FOR THE PRODUCTION OF MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | UDC IRELAND LIMITED (IE) | 2017-11-02 | — | — | US | disclosed |
| US-9718764-B2 | Synthetic building blocks for the production of materials for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2017-08-01 | — | — | US | disclosed |
| US-9718764-B2 | Synthetic building blocks for the production of materials for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2017-08-01 | — | — | US | disclosed |
| US-20160046563-A1 | SYNTHETIC BUILDING BLOCKS FOR THE PRODUCTION OF MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | UDC IRELAND LIMITED (IE) | 2016-02-18 | — | — | US | disclosed |
| US-20160046563-A1 | SYNTHETIC BUILDING BLOCKS FOR THE PRODUCTION OF MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | UDC IRELAND LIMITED (IE) | 2016-02-18 | — | — | US | disclosed |
| EP-2976322-A1 | SYNTHETIC BUILDING BLOCKS FOR THE PRODUCTION OF MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | Merck Patent GmbH (DE) | 2016-01-27 | — | — | EP | disclosed |
| WO-2014146750-A1 | SYNTHETIC BUILDING BLOCKS FOR THE PRODUCTION OF MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2014-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160046563-A1 | SYNTHETIC BUILDING BLOCKS FOR THE PRODUCTION OF MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | TBCB, CYBA, BMP2 | ALDH1A1 2033/4885ALOX15 1669/4885AKR1C3 3322/4885 |
| US-10407384-B2 | Synthetic building blocks for the production of materials for organic electroluminescence devices | TBCB, CYBA, BMP2 | ALDH1A1 2033/4885ALOX15 1669/4885AKR1C3 3322/4885 |
| US-20170313650-A1 | SYNTHETIC BUILDING BLOCKS FOR THE PRODUCTION OF MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | TBCB, CYBA, BMP2 | ALDH1A1 2033/4885ALOX15 1669/4885AKR1C3 3322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.