Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1610302 | 0.83 | NTSR1 (0.38) | MAPK1SMN1; SMN2TSHRNPC1RAB9A | |
| SCHEMBL1608874 | 0.82 | SLC6A3 (0.39) | ALDH1A1KDM4EMAPK1SMN1; SMN2LMNA | |
| SCHEMBL1609761 | 0.81 | RXRA (0.36) | ALDH1A1KDM4EMAPK1SMN1; SMN2LMNA | |
| SCHEMBL1609071 | 0.81 | SLC6A3 (0.33) | ALDH1A1KDM4EMAPK1SMN1; SMN2LMNA | |
| SCHEMBL1609778 | 0.78 | RBP4 (0.37) | CYP1A2CYP2C19MAPTTSHRMEN1 | |
| SCHEMBL1609555 | 0.78 | ALDH1A1 (0.36) | ALDH1A1KDM4EMAPK1SMN1; SMN2NPSR1 | |
| SCHEMBL1610187 | 0.78 | GAA (0.44) | ALDH1A1KDM4EMAPK1SMN1; SMN2NPSR1 | |
| SCHEMBL1609691 | 0.77 | SLC6A3 (0.42) | ALDH1A1KDM4EMAPK1SMN1; SMN2LMNA | |
| SCHEMBL1610229 | 0.77 | SLC6A3 (0.34) | ALDH1A1KDM4EMAPK1SMN1; SMN2LMNA | |
| SCHEMBL1609469 | 0.76 | PDE4D (0.36) | ALDH1A1KDM4ESMN1; SMN2NPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CBR3 | ALDH1A1 1562/4885KDM4E 2613/4885MAPK1 1418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.