SCHEMBL161189

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15204521	0.83	MAPT (0.38)	BCHEALDH1A1HPGDTSHRGAA
	SCHEMBL163215	0.77	P2RX4 (0.48)	P2RX4ALDH1A1SMN1; SMN2HPGDTSHR
	SCHEMBL163149	0.76	LPO (0.47)	BCHECA12CA1CA2CA7
	SCHEMBL160192	0.71	ALDH1A1 (0.44)	BCHEALDH1A1SMN1; SMN2HPGDTSHR
	SCHEMBL12431357	0.71	MAPT (0.40)	BCHEP2RX4CA12CA1CA2
	SCHEMBL162353	0.70	BCHE (0.46)	BCHEP2RX4ALDH1A1SMN1; SMN2TSHR
	SCHEMBL4176419	0.70	NOTUM (0.59)	BCHEP2RX4ALDH1A1SMN1; SMN2HPGD
	SCHEMBL164228	0.69	BCHE (0.51)	BCHEALDH1A1SMN1; SMN2HPGDTSHR
	SCHEMBL162055	0.69	BCHE (0.38)	BCHEP2RX4CA12CA1CA2
	SCHEMBL161488	0.69	—	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.