Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | FABP7 | O15540 | 2/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4423683 | 0.92 | KMT2A (0.70) | KMT2AEPHX2FABP7FABP5CASP3 | |
| SCHEMBL28617673 | 0.90 | KMT2A (0.67) | KMT2AEPHX2FABP7FABP5CASP3 | |
| SCHEMBL16790447 | 0.87 | KMT2A (0.62) | KMT2AEPHX2FABP7FABP5CASP3 | |
| SCHEMBL19450607 | 0.87 | KMT2A (0.64) | KMT2AEPHX2FABP7FABP5CASP3 | |
| SCHEMBL793384 | 0.87 | KMT2A (0.85) | KMT2AEPHX2FABP7FABP5CASP3 | |
| SCHEMBL163534 | 0.87 | KMT2A (0.67) | KMT2AEPHX2FABP7FABP5CASP3 | |
| SCHEMBL730784 | 0.85 | KMT2A (0.66) | KMT2AEPHX2FABP7FABP5CASP3 | |
| SCHEMBL6375583 | 0.85 | KMT2A (0.66) | KMT2AEPHX2FABP7FABP5CASP3 | |
| SCHEMBL1157227 | 0.85 | KMT2A (0.66) | KMT2AEPHX2FABP7FABP5CASP3 | |
| SCHEMBL92796 | 0.85 | KMT2A (0.66) | KMT2AEPHX2FABP7FABP5CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014153101-A2 | PEPTIDE AND PEPTIDE MIMETIC BINDING ANTAGONISTS OF POLO-LIKE KINASE 1 POLO BOX DOMAIN AND METHODS OF USE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES (US) | 2014-09-25 | — | — | WO | disclosed |