SCHEMBL28617673

SCHEMBL28617673

[O]CCNC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.67

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.67
EPHX2 P34913 1/20 0.54
FABP7 O15540 2/20 0.47
FABP5 Q01469 2/20 0.47
CASP3 P42574 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16119263 0.90 KMT2A (0.66) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL793384 0.88 KMT2A (0.85) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL163534 0.88 KMT2A (0.67) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL4752780 0.88 KMT2A (0.60) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL4423683 0.87 KMT2A (0.70) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL1157227 0.87 KMT2A (0.66) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL730784 0.87 KMT2A (0.66) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL92796 0.87 KMT2A (0.66) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL31419531 0.87 KMT2A (0.66) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL6375583 0.87 KMT2A (0.66) KMT2AEPHX2FABP7FABP5CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112533951-A anti-MSR 1 antibodies and methods of use thereof 里珍纳龙药品有限公司 2021-03-19 CN disclosed
CN-112004557-A Steroid compounds and antibody conjugates thereof 里珍纳龙药品有限公司 2020-11-27 CN disclosed
CN-101835498-B Method for preparing nanoparticles covered with a gem-bisphosphonate stabilizing layer coupled to hydrophilic biodistribution ligands 古尔比特公司 2016-08-24 CN disclosed
CN-101835498-A Novel method for the preparation of nanoparticles covered with a gem-bisphosphonate stabilizing layer coupled to hydrophilic biodistribution ligands GUERBET SA 2010-09-15 CN disclosed