SCHEMBL163534

SCHEMBL163534

O=C(NCCO)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.67

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.67
EPHX2 P34913 1/20 0.54
FABP7 O15540 2/20 0.47
FABP5 Q01469 2/20 0.47
CASP3 P42574 2/20 0.46
TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29468684 0.91 KMT2A (0.72) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL230688 0.91 KMT2A (0.72) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL31031901 0.91 KMT2A (0.72) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL1660910 0.90 KMT2A (0.74) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL29401182 0.89 KMT2A (0.77) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL6889085 0.89 KMT2A (0.77) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL887559 0.89 KMT2A (0.77) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL29458423 0.89 KMT2A (0.77) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL793384 0.88 KMT2A (0.85) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL28617673 0.88 KMT2A (0.67) KMT2AEPHX2FABP7FABP5CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 318 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344428-B Preparation method and application of tripterine glycoconjugate and nanoparticles 汕头大学医学院第一附属医院 2025-04-15 CN claimed
CN-118344428-A Preparation method and application of tripterine glycoconjugate and nanoparticles 汕头大学医学院第一附属医院 2024-07-16 CN claimed
EP-3125943-B1 PHOSPHATE BASED LINKERS FOR INTRACELLULAR DELIVERY OF DRUG CONJUGATES MERCK SHARP & DOHME LLC (US) 2026-04-22 EP disclosed
US-20260021196-A1 HOMOGENEOUS ANTIBODY-CONJUGATES WITH HIGH PAYLOAD LOADING SYNAFFIX BV (NL) 2026-01-22 US disclosed
US-12497460-B2 Anti-MSR1 antibodies and methods of use thereof REGENERON PHARMACEUTICALS, INC. (US) 2025-12-16 US disclosed
EP-4658318-A1 HOMOGENEOUS ANTIBODY-CONJUGATES WITH HIGH PAYLOAD LOADING Synaffix B.V. (NL) 2025-12-10 EP disclosed
US-12351652-B2 Hemagglutinin-binding peptide PEPTIDREAM INC. (JP) 2025-07-08 US disclosed
EP-4572795-A2 METHODS AND COMPOSITIONS FOR TREATING CANCER WITH CANCER-BINDING ADJUVANTS The University of Chicago (US) 2025-06-25 EP disclosed
WO-2025124486-A1 GLP-1 RECEPTOR COMPOUNDS, PREPARATION METHOD THEREFOR AND USE THEREOF 深圳信立泰药业股份有限公司 2025-06-19 WO disclosed
WO-2025098422-A1 MULTI-RECEPTOR CO-AGONIST COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF 深圳信立泰药业股份有限公司 2025-05-15 WO disclosed
WO-2025092778-A1 GLP-1 COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF 深圳信立泰药业股份有限公司 2025-05-08 WO disclosed
WO-1995005200-A1 DRUG DELIVERY AGENTS INCORPORATING MITOMYCIN EUROPEAN COMMUNITY (LU) 1995-02-23 WO disclosed
EP-0637309-A1 METAL COATINGS BIOCOMPATIBLES LIMITED (GB) 1995-02-08 EP disclosed
EP-0399330-B1 Modified phosphoramidite process for preparing modified nucleic acids BOEHRINGER MANNHEIM GMBH (DE) 1994-12-28 EP disclosed
EP-0601041-A1 POLYMER TREATMENTS BIOCOMPATIBLES LIMITED (GB) 1994-06-15 EP disclosed
WO-1993022320-A1 METAL COATINGS BIOCOMPATIBLES LIMITED (GB) 1993-11-11 WO disclosed
EP-0556216-A1 PHOSPHORIC ACID ESTERS AND THEIR USE IN THE PREPARATION OF BIOCOMPATIBLE SURFACES. BIOCOMPATIBLES LTD (GB) 1993-08-25 EP disclosed
WO-1993005081-A1 POLYMER TREATMENTS BIOCOMPATIBLES LTD. (GB) 1993-03-18 WO disclosed
WO-1992007858-A1 PHOSPHORIC ACID ESTERS AND THEIR USE IN THE PREPARATION OF BIOCOMPATIBLE SURFACES BIOCOMPATIBLES LIMITED (GB) 1992-05-14 WO disclosed
EP-0399330-A1 Modified phosphoramidite process for preparing modified nucleic acids Roche Diagnostics GmbH (DE) 1990-11-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260021196-A1 HOMOGENEOUS ANTIBODY-CONJUGATES WITH HIGH PAYLOAD LOADING FCGR2A, FCGR3B, FCGR1A KMT2A 1409/4885EPHX2 777/4885FABP7 4601/4885
US-12351652-B2 Hemagglutinin-binding peptide HGFAC, HM13, HIRA KMT2A 437/4885EPHX2 2653/4885FABP7 2308/4885
US-12497460-B2 Anti-MSR1 antibodies and methods of use thereof CD47, MSR1, LDLR KMT2A 710/4885EPHX2 4662/4885FABP7 396/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.