SCHEMBL1612103

SCHEMBL1612103

[C]#CC(C)c1ccccc1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.46
TSHR P16473 2/20 0.39
ACHE P22303 2/20 0.39
ACP3 P15309 1/20 0.36
SLC6A2 P23975 2/20 0.34
SLC6A4 P31645 2/20 0.34
SLC6A3 Q01959 2/20 0.34
GAA P10253 1/20 0.34
ADRA2A P08913 2/20 0.34
ADRA2B P18089 2/20 0.34
ADRA2C P18825 1/20 0.34
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
ALDH1A1 P00352 2/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
ADRB2 P07550 1/20 0.32
CYP2D6 P10635 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1610443 0.83 ADRA2A (0.42) ESR1TSHRACHESLC6A2ADRA2A
SCHEMBL954806 0.77 ESR1 (0.46) ESR1TSHRACHEACP3SLC6A2
SCHEMBL29433705 0.77 ESR1 (0.46) ESR1TSHRACHEACP3SLC6A2
SCHEMBL910441 0.77 ESR1 (0.46) ESR1TSHRACHEACP3SLC6A2
SCHEMBL9165861 0.77 ESR1 (0.46) ESR1TSHRACHEACP3SLC6A2
SCHEMBL1612296 0.74 CA1 (0.40) TSHRACHESLC6A4ALDH1A1CA1
SCHEMBL1611581 0.74 ALDH1A1 (0.37) SLC6A2GAAALDH1A1CHRM1ADRA1A
SCHEMBL1611190 0.74 TRPA1 (0.41) SLC6A2ALDH1A1CHRM1ADRA1AHTR2B
SCHEMBL1612475 0.74 ESR1 (0.39) ESR1TSHRACHEACP3SLC6A2
SCHEMBL624799 0.73 ESR1 (0.52) ESR1TSHRACHEACP3SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110087034-A1 Organic Semiconductor Material SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2011-04-14 US disclosed
EP-2248818-A1 ORGANIC SEMICONDUCTOR MATERIAL Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110087034-A1 Organic Semiconductor Material OR10J3, TST, OR51E2 ESR1 1107/4885TSHR 2994/4885ACHE 3944/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.