Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | FASN | P49327 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16122715 | 0.97 | GRM5 (0.39) | MAP4K4CYP11B1CYP11B2GABRG2GABRB3 | |
| SCHEMBL16122528 | 0.95 | CYP11B1 (0.44) | MAP4K4CYP11B1CYP11B2GABRG2GABRB3 | |
| SCHEMBL16122530 | 0.94 | CYP11B1 (0.46) | CYP11B1CYP11B2GABRG2GABRB3GABRA5 | |
| SCHEMBL16122531 | 0.86 | METAP2 (0.45) | CYP11B1CYP11B2KDM4EHPGDNPSR1 | |
| SCHEMBL16122293 | 0.80 | CYP11B1 (0.45) | MAP4K4CYP11B1CYP11B2KDM4EHPGD | |
| SCHEMBL17545813 | 0.80 | TRPV4 (0.35) | CYP11B1CYP11B2GRM5 | |
| SCHEMBL16122710 | 0.80 | CYP11B2 (0.41) | MAP4K4CYP11B1CYP11B2GRM5HPGD | |
| SCHEMBL17546156 | 0.78 | AR (0.40) | CYP11B1CYP11B2GRM5ARPGR | |
| SCHEMBL18411443 | 0.75 | HPGD (0.43) | CYP11B1CYP11B2GABRG2GABRB3GABRA5 | |
| SCHEMBL16122524 | 0.75 | TSHR (0.40) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2976322-B1 | SYNTHETIC BUILDING BLOCKS FOR THE PRODUCTION OF MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2019-11-20 | — | — | EP | disclosed |
| US-10407384-B2 | Synthetic building blocks for the production of materials for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2019-09-10 | — | — | US | disclosed |
| US-20170313650-A1 | SYNTHETIC BUILDING BLOCKS FOR THE PRODUCTION OF MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | UDC IRELAND LIMITED (IE) | 2017-11-02 | — | — | US | disclosed |
| US-9718764-B2 | Synthetic building blocks for the production of materials for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2017-08-01 | — | — | US | disclosed |
| US-20160046563-A1 | SYNTHETIC BUILDING BLOCKS FOR THE PRODUCTION OF MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | UDC IRELAND LIMITED (IE) | 2016-02-18 | — | — | US | disclosed |
| WO-2014146750-A1 | SYNTHETIC BUILDING BLOCKS FOR THE PRODUCTION OF MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2014-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160046563-A1 | SYNTHETIC BUILDING BLOCKS FOR THE PRODUCTION OF MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | TBCB, CYBA, BMP2 | MAP4K4 477/4885CYP11B1 1641/4885CYP11B2 1484/4885 |
| US-10407384-B2 | Synthetic building blocks for the production of materials for organic electroluminescence devices | TBCB, CYBA, BMP2 | MAP4K4 477/4885CYP11B1 1641/4885CYP11B2 1484/4885 |
| US-20170313650-A1 | SYNTHETIC BUILDING BLOCKS FOR THE PRODUCTION OF MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | TBCB, CYBA, BMP2 | MAP4K4 477/4885CYP11B1 1641/4885CYP11B2 1484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.