Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.46 |
| ▸ | PPARG | P37231 | 4/20 | 0.44 |
| ▸ | CTSK | P43235 | 9/20 | 0.42 |
| ▸ | CTSS | P25774 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13416738 | 0.86 | PPARA (0.43) | PPARAPPARGCTSKCTSSCYP1A2 | |
| SCHEMBL21837471 | 0.85 | PPARA (0.55) | PPARAPPARGCTSKCTSSCYP1A2 | |
| SCHEMBL21837472 | 0.85 | PPARA (0.55) | PPARAPPARGCTSKCTSSCYP1A2 | |
| SCHEMBL24633954 | 0.85 | PPARA (0.55) | PPARAPPARGCTSKCTSSCYP1A2 | |
| SCHEMBL3308623 | 0.84 | PPARA (0.42) | PPARAPPARGCTSKCTSSCYP1A2 | |
| SCHEMBL31386820 | 0.81 | CTSK (0.51) | PPARAPPARGCTSKCTSSCYP1A2 | |
| SCHEMBL16124741 | 0.79 | CTSK (0.35) | PPARAPPARGCTSKCTSSCYP1A2 | |
| SCHEMBL16124723 | 0.78 | PTGS1 (0.31) | CTSLCTSB | |
| SCHEMBL13416387 | 0.78 | PPARA (0.41) | PPARAPPARGCTSKCTSSCYP1A2 | |
| SCHEMBL13365298 | 0.77 | PPARA (0.53) | PPARAPPARGCTSKCTSSITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140288142-A1 | NITRIC OXIDE DONOR COMPOUNDS | NICOX SA (FR) | 2014-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140288142-A1 | NITRIC OXIDE DONOR COMPOUNDS | NOS3, NOS2, NOS1 | PPARA 2870/4885PPARG 3056/4885CTSK 4066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.