Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TMPRSS15 | P98073 | 4/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16124678 | 0.86 | MAPT (0.65) | MAPTALDH1A1TGM2THRBFAAH | |
| SCHEMBL16124652 | 0.85 | PPARA (0.50) | TMPRSS15 | |
| SCHEMBL16124607 | 0.85 | ITGB1 (0.55) | — | |
| SCHEMBL13416583 | 0.83 | CASP1 (0.43) | SUCNR1TMPRSS15PRSS1 | |
| SCHEMBL16124606 | 0.83 | GAA (0.49) | MAPTALDH1A1HPGDHSD17B10THRB | |
| SCHEMBL13396772 | 0.81 | CASP1 (0.42) | SUCNR1TMPRSS15PRSS1 | |
| SCHEMBL13416590 | 0.80 | TMPRSS15 (0.41) | SUCNR1TMPRSS15PRSS1 | |
| SCHEMBL21802397 | 0.79 | SLC1A3 (0.54) | MAPTSUCNR1FAAHGAATMPRSS15 | |
| SCHEMBL21802396 | 0.79 | SLC1A3 (0.54) | MAPTSUCNR1FAAHGAATMPRSS15 | |
| SCHEMBL13396750 | 0.78 | TMPRSS15 (0.40) | SUCNR1TMPRSS15PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140288142-A1 | NITRIC OXIDE DONOR COMPOUNDS | NICOX SA (FR) | 2014-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140288142-A1 | NITRIC OXIDE DONOR COMPOUNDS | NOS3, NOS2, NOS1 | MAPT 2611/4885ALDH1A1 360/4885HPGD 175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.