Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | DGKA | P23743 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6525769 | 0.93 | CA12 (0.43) | NPSR1MAPTMAPK1L3MBTL1CA12 | |
| SCHEMBL6525770 | 0.93 | CA12 (0.43) | NPSR1MAPTMAPK1L3MBTL1CA12 | |
| SCHEMBL13397085 | 0.91 | CA12 (0.42) | NPSR1MAPTMAPK1L3MBTL1NAAA | |
| SCHEMBL16124747 | 0.87 | NAAA (0.42) | NPSR1MAPTMAPK1L3MBTL1NAAA | |
| SCHEMBL1644712 | 0.87 | NAAA (0.55) | NPSR1MAPTMAPK1L3MBTL1NAAA | |
| SCHEMBL472925 | 0.87 | NAAA (0.55) | NPSR1MAPTMAPK1L3MBTL1NAAA | |
| SCHEMBL30179088 | 0.87 | NAAA (0.55) | NPSR1MAPTMAPK1L3MBTL1NAAA | |
| SCHEMBL15359687 | 0.86 | NOD1 (0.46) | NPSR1MAPTMAPK1L3MBTL1NAAA | |
| SCHEMBL16124746 | 0.85 | NOD1 (0.47) | NPSR1NAAAHTR2CRAD52NOD1 | |
| SCHEMBL2981700 | 0.85 | NAAA (0.58) | NPSR1MAPTMAPK1L3MBTL1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140288142-A1 | NITRIC OXIDE DONOR COMPOUNDS | NICOX SA (FR) | 2014-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140288142-A1 | NITRIC OXIDE DONOR COMPOUNDS | NOS3, NOS2, NOS1 | NPSR1 50/4885MAPT 2611/4885MAPK1 1298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.