SCHEMBL1613083

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20627981	0.85	CA12 (0.52)	CYP3A4MAPK1USP2SMN1; SMN2KMT2A
	SCHEMBL18324957	0.82	CYP3A4 (0.50)	CYP3A4MAPK1USP2SMN1; SMN2KMT2A
	SCHEMBL1662884	0.81	HMGCR (0.46)	CYP3A4MAPK1USP2SMN1; SMN2KMT2A
	SCHEMBL1612678	0.80	HPGDS (0.44)	CYP3A4MAPK1USP2SMN1; SMN2KMT2A
	SCHEMBL4743848	0.79	CYP3A4 (0.66)	CYP3A4MAPK1USP2SMN1; SMN2KMT2A
	SCHEMBL1661748	0.78	ALOX15 (0.38)	CYP3A4MAPK1USP2SMN1; SMN2KMT2A
	SCHEMBL12248741	0.75	CYP3A4 (0.60)	CYP3A4MAPK1USP2SMN1; SMN2KMT2A
	SCHEMBL28325906	0.75	AKR1B1 (0.52)	KMT2ALMNAGAAMAPTMET
	SCHEMBL2029772	0.75	CYP3A4 (0.78)	CYP3A4MAPK1USP2SMN1; SMN2KMT2A
	SCHEMBL12712826	0.75	HPGDS (0.40)	CYP3A4MAPK1USP2SMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.