Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 2/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 5/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23909099 | 0.85 | CNR2 (0.38) | NOS3NOS1NOS2HTR2CHTR2B | |
| SCHEMBL23966498 | 0.83 | NOS3 (0.39) | NOS3NOS1NOS2ALDH1A1CYP1A2 | |
| SCHEMBL23915543 | 0.81 | CNR2 (0.40) | NOS3NOS1NOS2HTR2CHTR2B | |
| SCHEMBL13475569 | 0.79 | HPGD (0.49) | TSHRHPGDMCHR1ELANEGAA | |
| SCHEMBL16135064 | 0.79 | MCHR1 (0.47) | CYP3A4TSHRMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL16135018 | 0.79 | CYP3A4 (0.38) | CYP3A4TSHRMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL20201699 | 0.79 | PDE10A (0.40) | RIPK1HPGDELANEHTR2CHTR2A | |
| SCHEMBL20201700 | 0.79 | ALDH1A1 (0.42) | ALDH1A1RIPK1HTR2CHTR2BPOLB | |
| SCHEMBL2561303 | 0.77 | NOS3 (0.44) | NOS3NOS1NOS2ALDH1A1RIPK1 | |
| SCHEMBL16134990 | 0.77 | CYP3A4 (0.39) | CYP3A4TSHRMAPK1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9309191-B2 | Amidine compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-04-12 | — | — | US | disclosed |
| US-9309191-B2 | Amidine compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-04-12 | — | — | US | disclosed |
| US-9309191-B2 | Amidine compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-04-12 | — | — | US | disclosed |
| US-20160046564-A1 | AMIDINE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-02-18 | — | — | US | disclosed |
| WO-2014157596-A1 | AMIDINE COMPOUND AND USE THEREOF | 住友化学株式会社 (JP) | 2014-10-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160046564-A1 | AMIDINE COMPOUND AND USE THEREOF | ARGLU1, ARG1, PRMT1 | CYP3A4 1871/4885TSHR 162/4885MAPK1 477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.