Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1613577 | 1.00 | ALOX15 (0.54) | ALOX15ALDH1A1TSHRPRKCALMNA | |
| SCHEMBL31538381 | 0.90 | ALOX15 (0.51) | ALOX15ALDH1A1PRKCA | |
| SCHEMBL31538310 | 0.89 | ALOX15 (0.50) | ALOX15ALDH1A1PRKCA | |
| SCHEMBL31538327 | 0.88 | ALOX15 (0.49) | ALOX15ALDH1A1PRKCA | |
| SCHEMBL31538392 | 0.88 | ALOX15 (0.49) | ALOX15ALDH1A1PRKCA | |
| SCHEMBL31538335 | 0.88 | ALOX15 (0.49) | ALOX15ALDH1A1PRKCA | |
| SCHEMBL31538353 | 0.86 | ALOX15 (0.53) | ALOX15ALDH1A1TSHRLMNAHSD17B10 | |
| SCHEMBL31549474 | 0.84 | FAAH (0.39) | ALOX15TAS1R3TAS1R1PGR | |
| SCHEMBL7948558 | 0.79 | FFAR1 (0.50) | ALOX15ALDH1A1LMNAHSD17B10PGR | |
| SCHEMBL7556359 | 0.79 | FFAR1 (0.50) | ALOX15ALDH1A1LMNAHSD17B10PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8344023-B2 | 2,5-di- and 2,2,5-trisubstituted di- and tetrahydrofuran derivatives and their use for the production of perfumes | GIVAUDAN SA (CH) | 2013-01-01 | — | — | US | disclosed |
| EP-2155844-B1 | PERFUME SYSTEMS | PROCTER & GAMBLE (US) | 2012-11-21 | — | — | EP | disclosed |
| US-8278230-B2 | Perfume systems | THE PROCTER & GAMBLE COMPANY (US) | 2012-10-02 | — | — | US | disclosed |
| EP-2152682-B1 | 2,5-DI- AND 2,2,5-TRISUBSTITUTED DI- AND TETRAHYDROFURAN DERIVATIVES AND THEIR USE FOR THE PRODUCTION OF PERFUMES | GIVAUDAN SA (CH) | 2011-08-17 | — | — | EP | disclosed |
| US-20110086793-A1 | PERFUME SYSTEMS | THE PROCTER & GAMBLE COMPANY (US) | 2011-04-14 | — | — | US | disclosed |
| US-20100173999-A1 | 2,5-DI- and 2,2,5-Trisubstituted Di- and Tetrahydrofuran Derivatives and Their Use for the Production of Perfumes | GIVAUDAN SA (CH) | 2010-07-08 | — | — | US | disclosed |
| EP-2155844-A2 | PERFUME SYSTEMS | The Procter and Gamble Company (US) | 2010-02-24 | — | — | EP | disclosed |
| EP-2152682-A1 | 2,5-DI- AND 2,2,5-TRISUBSTITUTED DI- AND TETRAHYDROFURAN DERIVATIVES AND THEIR USE FOR THE PRODUCTION OF PERFUMES | Givaudan SA (CH) | 2010-02-17 | — | — | EP | disclosed |
| US-20080305977-A1 | PERFUME SYSTEMS | THE PROCTER & GAMBLE COMPANY (US) | 2008-12-11 | — | — | US | disclosed |
| WO-2008148236-A1 | 2,5-DI- AND 2,2,5-TRISUBSTITUTED DI- AND TETRAHYDROFURAN DERIVATIVES AND THEIR USE FOR THE PRODUCTION OF PERFUMES | GIVAUDAN SA (CH) | 2008-12-11 | — | — | WO | disclosed |
| WO-2008151273-A2 | PERFUME SYSTEMS | THE PROCTER & GAMBLE COMPANY (US) | 2008-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173999-A1 | 2,5-DI- and 2,2,5-Trisubstituted Di- and Tetrahydrofuran Derivatives and Their Use for the Production of Perfumes | COXFA4, DUOX2, DRD5 | ALOX15 756/4885ALDH1A1 733/4885TSHR 4484/4885 |
| US-20110086793-A1 | PERFUME SYSTEMS | PAOX, PLIN5, PFKFB2 | ALOX15 525/4885ALDH1A1 2656/4885TSHR 4682/4885 |
| US-20080305977-A1 | PERFUME SYSTEMS | PAOX, PLIN5, PFKFB2 | ALOX15 525/4885ALDH1A1 2656/4885TSHR 4682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.