Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | EBP | Q15125 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.38 |
| ▸ | CCR1 | P32246 | 4/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 6/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29134294 | 0.80 | CASP1 (0.35) | — | |
| SCHEMBL28462710 | 0.79 | ATM (0.39) | DRD2DRD4OPRM1DRD3CYP2D6 | |
| SCHEMBL27976101 | 0.79 | CCR1 (0.43) | DRD2DRD4OPRM1DRD3CYP2D6 | |
| SCHEMBL14541984 | 0.79 | EBP (0.51) | DRD2DRD4OPRM1DRD3CYP2D6 | |
| SCHEMBL28481925 | 0.79 | DRD2 (0.59) | DRD2DRD4OPRM1DRD3CYP2D6 | |
| SCHEMBL9774391 | 0.79 | CASP1 (0.51) | DRD2DRD4OPRM1DRD3CYP2D6 | |
| SCHEMBL11075302 | 0.79 | CYP2C19 (0.40) | DRD2DRD4OPRM1DRD3CYP2D6 | |
| SCHEMBL5476420 | 0.78 | KCNN4 (0.41) | ATMCHRM3 | |
| SCHEMBL5476864 | 0.78 | CTSK (0.41) | — | |
| SCHEMBL5475919 | 0.76 | CYP4F2 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9029547-B1 | Synthesis of 4-aryl 4-acyl piperidine, its salts and analogs using indium metal | SAMI LABS LIMITED (IN) | 2015-05-12 | — | — | US | disclosed |
| US-8853407-B1 | Synthesis of 4-aryl 4-acyl piperidine, its salts and analogs using indium metal | SAMI LABS LIMITED (IN) | 2014-10-07 | — | — | US | disclosed |
| CN-103936665-A | Synthesis method of 4-substituted piperidine derivatives | 63975 PLA TROOPS | 2014-07-23 | — | — | CN | disclosed |