SCHEMBL1613781

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1669586	0.85	PIM1 (0.56)	PIM1PPARGALDH1A1DVL1ENPP2
	SCHEMBL1614943	0.84	PIM1 (0.53)	PIM1PPARGALDH1A1NLRP3SLC2A1
	SCHEMBL1614720	0.83	SLC2A1 (0.65)	PIM1PPARGALDH1A1NLRP3SLC2A1
	SCHEMBL12712452	0.81	PIM1 (0.50)	PIM1PPARGALDH1A1NLRP3SLC2A1
	SCHEMBL12712433	0.80	SLC2A1 (0.56)	PIM1PPARGALDH1A1NLRP3SLC2A1
	SCHEMBL1614757	0.80	ENPP2 (0.61)	PPARGALDH1A1ENPP2MEN1KMT2A
	SCHEMBL8689406	0.77	PIM1 (0.44)	PIM1ALDH1A1MEN1KMT2A
	SCHEMBL1614334	0.73	ENPP2 (0.54)	PIM1PPARGALDH1A1ENPP2MEN1
	SCHEMBL2174422	0.72	SLC2A1 (0.60)	PIM1PPARGALDH1A1NLRP3SLC2A1
	SCHEMBL12406528	0.72	SLC2A1 (0.60)	PIM1PPARGALDH1A1NLRP3SLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.