Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 15/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL1244938 | 0.99 | INSR (0.50) | INSRTAAR1MAPTAPPMEN1 | |
| Hydrochloric Acid SCHEMBL1243591 | 0.84 | INSR (0.52) | INSRTAAR1MAPTHTTPOLB | |
| SCHEMBL17366641 | 0.74 | CYP2D6 (0.54) | INSRMAPTMEN1HTTKMT2A | |
| Iodide SCHEMBL1243530 | 0.70 | INSR (0.53) | INSRTAAR1MAPTHTTPOLB | |
| SCHEMBL1244922 | 0.70 | ALOX5 (0.61) | INSRTAAR1MAPTAPPMEN1 | |
| Iodide SCHEMBL8723044 | 0.70 | INSR (0.69) | INSRMAPTAPPMEN1HTT | |
| Iodide SCHEMBL1245586 | 0.69 | INSR (0.37) | INSRAPPMEN1HTTKMT2A | |
| SCHEMBL34468132 | 0.68 | INSR (0.72) | INSRMAPTAPPMEN1HTT | |
| SCHEMBL1246538 | 0.68 | ACHE (0.58) | TAAR1MAPTMEN1HTTKMT2A | |
| SCHEMBL13294091 | 0.68 | INSR (0.42) | INSRMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2459733-B1 | NOVEL PEPTIDASE SUBSTRATES | BIOMERIEUX SA (FR) | 2014-10-08 | — | — | EP | disclosed |