Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625677 | 0.95 | ALDH1A1 (0.54) | LTA4HAKR1C3ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL10320300 | 0.92 | ALDH1A1 (0.58) | LTA4HAKR1C3ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL133561 | 0.92 | ALDH1A1 (0.58) | LTA4HAKR1C3ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL14345952 | 0.89 | AKR1C3 (0.57) | LTA4HAKR1C3ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL28356161 | 0.86 | ALDH1A1 (0.59) | ALDH1A1MAPTL3MBTL1ALOX15KDM4E | |
| SCHEMBL24518338 | 0.85 | CHKA (0.62) | AKR1C3ALDH1A1MAPTKDM4ENPC1 | |
| SCHEMBL17642581 | 0.83 | AKR1C3 (0.57) | LTA4HAKR1C3ALDH1A1MAPTALOX15 | |
| SCHEMBL14863377 | 0.81 | LTA4H (0.69) | LTA4HALDH1A1KDM4ELMNA | |
| SCHEMBL2088597 | 0.81 | LTA4H (0.42) | LTA4HAKR1C3ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL1432961 | 0.80 | AKR1C3 (0.65) | LTA4HAKR1C3ALDH1A1MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10259800-B2 | Method of fluorination using iodonium ylides | THE GENERAL HOSPITAL CORPORATION (US) | 2019-04-16 | — | — | US | disclosed |
| US-20170121300-A1 | METHOD OF FLUORINATION USING IODONIUM YLIDES | THE GENERAL HOSPITAL CORPORATION | 2017-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170121300-A1 | METHOD OF FLUORINATION USING IODONIUM YLIDES | FLI1, ABL1, PFAS | LTA4H 2343/4885AKR1C3 2092/4885ALDH1A1 2216/4885 |
| US-10259800-B2 | Method of fluorination using iodonium ylides | FLI1, ABL1, PFAS | LTA4H 2343/4885AKR1C3 2092/4885ALDH1A1 2216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.