Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LGMN | Q99538 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14345952 | 0.83 | AKR1C3 (0.57) | MAPTALDH1A1LTA4HAKR1C3THRB | |
| SCHEMBL12490848 | 0.79 | ALDH1A1 (0.56) | MAPTALDH1A1LGMNAKR1C3THRB | |
| SCHEMBL625677 | 0.78 | ALDH1A1 (0.54) | MAPTALDH1A1LTA4HAKR1C3THRB | |
| SCHEMBL18815076 | 0.78 | LTA4H (0.52) | MAPTALDH1A1LTA4HAKR1C3THRB | |
| SCHEMBL3035197 | 0.77 | LGMN (0.60) | MAPTALDH1A1LGMNAKR1C3THRB | |
| SCHEMBL16611429 | 0.77 | MAPT (0.53) | MAPTALDH1A1LGMNAKR1C3THRB | |
| SCHEMBL9362762 | 0.77 | MAPT (0.53) | MAPTALDH1A1LGMNAKR1C3THRB | |
| SCHEMBL3168651 | 0.77 | ALDH1A1 (0.57) | MAPTALDH1A1LGMNDRD4HTT | |
| SCHEMBL8648308 | 0.77 | ADRB1 (0.57) | MAPTALDH1A1LGMNAKR1C3MEN1 | |
| SCHEMBL133561 | 0.76 | ALDH1A1 (0.58) | MAPTALDH1A1LTA4HAKR1C3THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017093544-A1 | ALKYNYL PHOSPHINE GOLD COMPLEXES FOR TREATING BACTERIAL INFECTIONS | AUSPHERIX LIMITED (GB) | 2017-06-08 | — | — | WO | disclosed |
| WO-2016201370-A1 | COMBINATION THERAPY OF TRANSCRIPTION INHIBITORS AND KINASE INHIBITORS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2016-12-15 | — | — | WO | disclosed |
| WO-2016022970-A1 | DIHYDROPTERIDINONE DERIVATIVES AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2016-02-11 | — | — | WO | disclosed |