Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | HTT | P42858 | 3/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 14/20 | 0.63 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.62 |
| ▸ | HTR2B | P41595 | 1/20 | 0.62 |
| ▸ | PAK1 | Q13153 | 2/20 | 0.61 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | BTK | Q06187 | 1/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30523405 | 1.00 | LMNA (0.63) | LMNAHTTPKMHSD17B10ADORA3 | |
| SCHEMBL16146499 | 0.83 | ADORA3 (0.67) | LMNAHTTPKMHSD17B10ADORA3 | |
| SCHEMBL30523434 | 0.83 | LMNA (0.63) | LMNAHTTPKMHSD17B10ADORA3 | |
| SCHEMBL16146753 | 0.83 | LMNA (0.63) | LMNAHTTPKMHSD17B10ADORA3 | |
| SCHEMBL1803031 | 0.83 | LMNA (0.63) | LMNAHTTPKMHSD17B10ADORA3 | |
| SCHEMBL3451451 | 0.83 | LMNA (0.63) | LMNAHTTPKMHSD17B10ADORA3 | |
| SCHEMBL797051 | 0.83 | LMNA (0.63) | LMNAHTTPKMHSD17B10ADORA3 | |
| SCHEMBL16146720 | 0.83 | LMNA (0.63) | LMNAHTTPKMHSD17B10ADORA3 | |
| SCHEMBL16146912 | 0.83 | LMNA (0.63) | LMNAHTTPKMHSD17B10ADORA3 | |
| SCHEMBL7621600 | 0.81 | LMNA (0.62) | LMNAHTTPKMHSD17B10ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140303112-A1 | Method for treating disease or condition susceptible to amelioration by AMPK activators and compounds of formula which are useful to activate AMP-activated protein kinase (AMPK) | ENERGENESIS BIOMEDICAL CO., LTD (TW) | 2014-10-09 | — | — | US | claimed |
| US-9938279-B2 | Method for treating disease or condition susceptible to amelioration by AMPK activators and compounds of formula which are useful to activate AMP-activated protein kinase (AMPK) | ENERGENESIS BIOMEDICAL CO., LTD (TW) | 2018-04-10 | — | — | US | disclosed |
| US-20140303112-A1 | Method for treating disease or condition susceptible to amelioration by AMPK activators and compounds of formula which are useful to activate AMP-activated protein kinase (AMPK) | ENERGENESIS BIOMEDICAL CO., LTD (TW) | 2014-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140303112-A1 | Method for treating disease or condition susceptible to amelioration by AMPK activators and compounds of formula which are useful to activate AMP-activated protein kinase (AMPK) | PRKAG2, PRKAB2, PRKAG1 | LMNA 599/4885HTT 3291/4885PKM 91/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.