Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL143121 | 1.00 | TRPM8 (0.48) | TRPM8HTTFOLH1CASP1SYK | |
| SCHEMBL5197791 | 0.87 | CASP1 (0.52) | TRPM8CASP1SYKCTSLCTSS | |
| SCHEMBL5196289 | 0.86 | TRPM8 (0.47) | TRPM8HTTFOLH1CASP1SYK | |
| SCHEMBL15132856 | 0.82 | HTT (0.50) | TRPM8HTTFOLH1CASP1CTSL | |
| SCHEMBL11227787 | 0.82 | HTT (0.52) | TRPM8HTTFOLH1CASP1ATM | |
| SCHEMBL10827930 | 0.81 | CTSK (0.55) | CTSLCTSSCTSBATMCTSK | |
| SCHEMBL11255815 | 0.80 | HTT (0.56) | HTTFOLH1CASP1CTSLCTSS | |
| SCHEMBL144787 | 0.79 | ATM (0.42) | TRPM8HTTFOLH1SYKCTSL | |
| SCHEMBL1643448 | 0.79 | CTSK (0.52) | TRPM8SYKCTSLCTSSCTSB | |
| SCHEMBL265046 | 0.79 | ATM (0.56) | HTTFOLH1CTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9737621-B2 | MRI-visible hydrophobic copolymer | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2017-08-22 | — | — | US | disclosed |
| US-20140302324-A1 | MRI-VISIBLE HYDROPHOBIC COPOLYMER | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140302324-A1 | MRI-VISIBLE HYDROPHOBIC COPOLYMER | PHF6, CD14, PGRMC2 | TRPM8 2447/4885HTT 145/4885FOLH1 493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.