Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7571189 | 0.77 | ADAM17 (0.33) | CA2CA1 | |
| SCHEMBL2167085 | 0.76 | CA2 (0.31) | CA2 | |
| SCHEMBL2167842 | 0.73 | ALDH1A1 (0.31) | — | |
| SCHEMBL17222829 | 0.73 | CA2 (0.36) | CA2CA1 | |
| SCHEMBL20191736 | 0.72 | CA2 (0.38) | CA2CA1 | |
| SCHEMBL577322 | 0.71 | CA2 (0.35) | CA2CA1 | |
| SCHEMBL27622033 | 0.71 | CA2 (0.35) | CA2CA1 | |
| Ammonia Solution, Strong SCHEMBL27888161 | 0.70 | CA2 (0.37) | CA2CA1 | |
| SCHEMBL132592 | 0.69 | CA2 (0.42) | CA2CA1 | |
| Hydrogen Sulfide SCHEMBL30604704 | 0.67 | CA2 (0.41) | CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11634449-B2 | Macrolides and methods of their preparation and use | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-04-25 | — | — | US | disclosed |
| EP-4095146-A1 | MACROLIDES AND METHODS OF THEIR PREPARATION AND USE | President And Fellows Of Harvard College (US) | 2022-11-30 | — | — | EP | disclosed |
| US-20220332747-A1 | MACROLIDES AND METHODS OF THEIR PREPARATION AND USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2022-10-20 | — | — | US | disclosed |
| EP-2988597-B1 | MACROLIDES AND METHODS OF THEIR PREPARATION AND USE | HARVARD COLLEGE (US) | 2022-06-08 | — | — | EP | disclosed |
| US-10913764-B2 | Macrolides and methods of their preparation and use | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-02-09 | — | — | US | disclosed |
| CN-111825733-A | Macrolides and methods of making and using the same | 哈佛大学的校长及成员们 | 2020-10-27 | — | — | CN | disclosed |
| US-20180298048-A1 | MACROLIDES AND METHODS OF THEIR PREPARATION AND USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-10-18 | — | — | US | disclosed |
| US-9982005-B2 | Macrolides and methods of their preparation and use | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-05-29 | — | — | US | disclosed |
| EP-2988597-A2 | MACROLIDES AND METHODS OF THEIR PREPARATION AND USE | President and Fellows of Harvard College (US) | 2016-03-02 | — | — | EP | disclosed |
| US-20160052951-A1 | MACROLIDES AND METHODS OF THEIR PREPARATION AND USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-02-25 | — | — | US | disclosed |
| WO-2014165792-A2 | MACROLIDES AND METHODS OF THEIR PREPARATION AND USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220332747-A1 | MACROLIDES AND METHODS OF THEIR PREPARATION AND USE | CYP11B2, ERG28, DHCR7 | CA2 4851/4885CA1 4869/4885 |
| US-20160052951-A1 | MACROLIDES AND METHODS OF THEIR PREPARATION AND USE | CYP11B2, ERG28, DHCR7 | CA2 4851/4885CA1 4869/4885 |
| US-11634449-B2 | Macrolides and methods of their preparation and use | CYP11B2, ERG28, DHCR7 | CA2 4851/4885CA1 4869/4885 |
| US-10913764-B2 | Macrolides and methods of their preparation and use | CYP11B2, ERG28, DHCR7 | CA2 4851/4885CA1 4869/4885 |
| US-20180298048-A1 | MACROLIDES AND METHODS OF THEIR PREPARATION AND USE | CYP11B2, ERG28, DHCR7 | CA2 4851/4885CA1 4869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.