Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TOP1 | P11387 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.49 |
| ▸ | WDR5 | P61964 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7343390 | 0.83 | KMT2A (0.72) | PYGLKMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL16147456 | 0.80 | KCNMA1 (0.67) | PYGLHDAC1HDAC8HDAC6KMT2A | |
| SCHEMBL20601819 | 0.79 | WDR5 (0.54) | PYGLHDAC1HDAC8HDAC6KMT2A | |
| SCHEMBL20601662 | 0.79 | PYGL (0.82) | PYGLHDAC1HDAC8HDAC6KMT2A | |
| Benzene SCHEMBL7447284 | 0.79 | ALDH1A1 (0.70) | PYGLKMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL3134272 | 0.79 | ALDH1A1 (0.58) | PYGLHDAC8KMT2AKDM4EALDH1A1 | |
| SCHEMBL16392552 | 0.78 | PYGL (0.48) | PYGLHDAC1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5316685 | 0.77 | HTT (0.59) | PYGLKMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL7344448 | 0.77 | PYGL (0.58) | PYGLKMT2AALDH1A1TOP1NPC1 | |
| SCHEMBL5233294 | 0.77 | ALDH1A1 (0.56) | PYGLKMT2AKDM4EALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014165816-A1 | COMPOUNDS USEFUL FOR THE TREATMENT OF METABOLIC DISORDERS AND SYNTHESIS OF THE SAME | NORTH CAROLINA CENTRAL UNIVERSITY (US) | 2014-10-09 | — | — | WO | disclosed |