Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KCNJ11 | Q14654 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.33 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.33 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16150471 | 0.90 | SMN1; SMN2 (0.39) | ALDH1A1SMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16150200 | 0.88 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2RORCMEN1KMT2A | |
| SCHEMBL16151279 | 0.84 | HTT (0.45) | ALDH1A1SMN1; SMN2RORCMEN1KMT2A | |
| SCHEMBL16151303 | 0.83 | KCNJ11 (0.41) | ALDH1A1SMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16150507 | 0.81 | KCNJ11 (0.42) | ALDH1A1SMN1; SMN2RORCMEN1KMT2A | |
| SCHEMBL20428917 | 0.81 | PDK1 (0.41) | ALDH1A1SMN1; SMN2RORCMEN1KMT2A | |
| SCHEMBL16150837 | 0.81 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2RORCMEN1KMT2A | |
| SCHEMBL16150675 | 0.79 | KCNJ11 (0.38) | ALDH1A1SMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16155858 | 0.78 | KCNJ11 (0.40) | ALDH1A1SMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8773837 | 0.77 | POLB (0.42) | ALDH1A1SMN1; SMN2RORCMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2981519-B1 | PROCESS FOR THE PREPARATION OF AMIDES FROM HINDERED ANILINES CONTAINING A PERHALOALKYL GROUP | SYNGENTA PARTICIPATIONS AG (CH) | 2018-08-01 | — | — | EP | disclosed |
| US-9598369-B2 | Process for the preparation of amides from hindered anilines containing a perhaloalkyl group | SYNGENTA PARTICIPATIONS AG (CH) | 2017-03-21 | — | — | US | disclosed |
| US-9598369-B2 | Process for the preparation of amides from hindered anilines containing a perhaloalkyl group | SYNGENTA PARTICIPATIONS AG (CH) | 2017-03-21 | — | — | US | disclosed |
| US-9598369-B2 | Process for the preparation of amides from hindered anilines containing a perhaloalkyl group | SYNGENTA PARTICIPATIONS AG (CH) | 2017-03-21 | — | — | US | disclosed |
| US-20160168097-A1 | PROCESS FOR THE PREPARATION OF AMIDES FROM HINDERED ANILINES CONTAINING A PERHALOALKYL GROUP | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-16 | — | — | US | disclosed |
| US-20160168097-A1 | PROCESS FOR THE PREPARATION OF AMIDES FROM HINDERED ANILINES CONTAINING A PERHALOALKYL GROUP | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-16 | — | — | US | disclosed |
| US-20160168097-A1 | PROCESS FOR THE PREPARATION OF AMIDES FROM HINDERED ANILINES CONTAINING A PERHALOALKYL GROUP | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-16 | — | — | US | disclosed |
| EP-2981519-A1 | PROCESS FOR THE PREPARATION OF AMIDES FROM HINDERED ANILINES CONTAINING A PERHALOALKYL GROUP | Syngenta Participations AG (CH) | 2016-02-10 | — | — | EP | disclosed |
| WO-2014161850-A1 | PROCESS FOR THE PREPARATION OF AMIDES FROM HINDERED ANILINES CONTAINING A PERHALOALKYL GROUP | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168097-A1 | PROCESS FOR THE PREPARATION OF AMIDES FROM HINDERED ANILINES CONTAINING A PERHALOALKYL GROUP | ABHD5, FADS1, PFAS | ALDH1A1 969/4885SMN1; SMN2 4697/4885RORC 4587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.