SCHEMBL1615072

SCHEMBL1615072

COc1ccc(-c2ccc(OC)cc2-c2ccccc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.63
ABCB1 P08183 1/20 0.63
BCR P11274 1/20 0.63
BACE1 P56817 3/20 0.61
SMN1; SMN2 Q16637 3/20 0.56
KDM4E B2RXH2 4/20 0.54
NPC1 O15118 3/20 0.54
ALDH1A1 P00352 3/20 0.54
RAB9A P51151 3/20 0.54
ACACA Q13085 1/20 0.54
MITF O75030 1/20 0.54
HTT P42858 1/20 0.54
PTPN1 P18031 1/20 0.54
CYP1A2 P05177 2/20 0.52
CYP2D6 P10635 2/20 0.52
CYP2C9 P11712 2/20 0.52
CYP2C19 P33261 2/20 0.52
CYP1A1 P04798 1/20 0.52
CYP2E1 P05181 1/20 0.52
CYP3A4 P08684 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29402037 0.96 PTPN1 (0.57) ABL1ABCB1BCRBACE1SMN1; SMN2
SCHEMBL5551697 0.96 PTPN1 (0.57) ABL1ABCB1BCRBACE1SMN1; SMN2
Hydrogen Sulfide SCHEMBL27936907 0.94 PTPN1 (0.56) ABL1ABCB1BCRBACE1SMN1; SMN2
SCHEMBL12325013 0.92 PTPN1 (0.57) ABL1ABCB1BCRBACE1SMN1; SMN2
SCHEMBL22079638 0.91 NPC1 (0.54) ABL1ABCB1BCRBACE1SMN1; SMN2
SCHEMBL10802577 0.90 ABL1 (0.61) ABL1ABCB1BCRBACE1SMN1; SMN2
Formic Acid SCHEMBL29173687 0.90 BACE1 (0.55) ABL1ABCB1BCRBACE1SMN1; SMN2
SCHEMBL12770828 0.89 NPC1 (0.56) ABL1ABCB1BCRBACE1SMN1; SMN2
SCHEMBL11819228 0.87 ABL1 (0.73) ABL1ABCB1BCRBACE1SMN1; SMN2
SCHEMBL15271344 0.85 ABL1 (0.56) ABL1ABCB1BCRBACE1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12082493-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-09-03 US disclosed
US-20230320196-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-05 US disclosed
US-11690286-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-06-27 US disclosed
US-20210167292-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-06-03 US disclosed
US-10957858-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-03-23 US disclosed
EP-3159333-B1 BENZO-FUSED THIOPHENE OR FURAN COMPOUNDS COMPRISING A TRIPHENYLENE GROUP UNIVERSAL DISPLAY CORP (US) 2020-04-22 EP disclosed
US-20190245147-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-08-08 US disclosed
US-10374171-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-08-06 US disclosed
US-10312450-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-06-04 US disclosed
EP-3424918-A1 SINGLE TRIPHENYLENE CHROMOPHORES IN PHOSPHORESCENT LIGHT EMITTING DIODES Universal Display Corporation (US) 2019-01-09 EP disclosed
EP-2200956-B1 SINGLE TRIPHENYLENE CHROMOPHORES IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORP (US) 2013-07-03 EP disclosed
US-8367850-B2 Benzo-fused thiophene or benzo-fused furan compounds comprising a triphenylene group UNIVERSAL DISPLAY CORPORATION (US) 2013-02-05 US disclosed
EP-2511254-A2 Single triphenylene chromophores in phosphorescent light emitting diodes Universal Display Corporation (US) 2012-10-17 EP disclosed
US-20110084599-A1 SINGLE TRIPHENYLENE CHROMOPHORES IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2011-04-14 US disclosed
US-20100237334-A1 Benzo-Fused Thiophene or Bezon-Fused Furan Compounds Comprising a Triphenylene Group UNIVERSAL DISPLAY CORPORATION (US) 2010-09-23 US disclosed
EP-2200956-A1 SINGLE TRIPHENYLENE CHROMOPHORES IN PHOSPHORESCENT LIGHT EMITTING DIODES Universal Display Corporation (US) 2010-06-30 EP disclosed
EP-2185532-A2 BENZO-FUSED THIOPHENE OR BENZO-FUSED FURAN COMPOUNDS COMPRISING A TRIPHENYLENE GROUP Universal Display Corporation (US) 2010-05-19 EP disclosed
WO-2009021126-A9 BENZO-FUSED THIOPHENE OR BENZO-FUSED FURAN COMPOUNDS COMPRISING A TRIPHENYLENE GROUP UNIVERSAL DISPLAY CORPORATION (US) 2009-09-11 WO disclosed
WO-2009021126-A2 BENZO-FUSED THIOPHENE OR BENZO-FUSED FURAN COMPOUNDS COMPRISING A TRIPHENYLENE GROUP UNIVERSAL DISPLAY CORPORATION (US) 2009-02-12 WO disclosed
WO-2009021107-A1 SINGLE TRIPHENYLENE CHROMOPHORES IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-02-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12082493-B2 Organic electroluminescent materials and devices NONO, ORC3, TYR ABL1 1981/4885ABCB1 3523/4885BCR 565/4885
US-10312450-B2 Organic electroluminescent materials and devices NONO, ORC3, LEF1 ABL1 1827/4885ABCB1 3019/4885BCR 592/4885
US-20110084599-A1 SINGLE TRIPHENYLENE CHROMOPHORES IN PHOSPHORESCENT LIGHT EMITTING DIODES TYR, PNP, MAPRE2 ABL1 946/4885ABCB1 2541/4885BCR 598/4885
US-20230320196-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NONO, ORC3, TYR ABL1 1981/4885ABCB1 3523/4885BCR 565/4885
US-10957858-B2 Organic electroluminescent materials and devices NONO, ORC3, LEF1 ABL1 1827/4885ABCB1 3019/4885BCR 592/4885
US-11690286-B2 Organic electroluminescent materials and devices NONO, ORC3, LEF1 ABL1 1827/4885ABCB1 3019/4885BCR 592/4885
US-20100237334-A1 Benzo-Fused Thiophene or Bezon-Fused Furan Compounds Comprising a Triphenylene Group TFEB, BRD4, TEC ABL1 540/4885ABCB1 312/4885BCR 682/4885
US-20210167292-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NONO, ORC3, LEF1 ABL1 1827/4885ABCB1 3019/4885BCR 592/4885
US-20190245147-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NONO, ORC3, LEF1 ABL1 1827/4885ABCB1 3019/4885BCR 592/4885
US-10374171-B2 Organic electroluminescent materials and devices TPR, EED, TEAD2 ABL1 983/4885ABCB1 1057/4885BCR 2089/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.