SCHEMBL161509

SCHEMBL161509

FC(F)(F)c1ccc2ccsc2c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 1/20 0.45
PTPN6 P29350 1/20 0.45
PTPN11 Q06124 1/20 0.45
PTPN22 Q9Y2R2 1/20 0.45
EPHX2 P34913 1/20 0.44
SCN4A P35499 1/20 0.44
PTPN5 P54829 1/20 0.39
BACE1 P56817 1/20 0.39
METAP2 P50579 1/20 0.39
MPL P40238 2/20 0.37
DYRK1A Q13627 1/20 0.36
ACE2 Q9BYF1 1/20 0.36
KDM4E B2RXH2 1/20 0.35
FBP1 P09467 1/20 0.35
PPARA Q07869 1/20 0.34
CYP2A6 P11509 2/20 0.33
CES2 O00748 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL696472 0.85 KIF11 (0.44) PTPRCPTPN6PTPN11PTPN22DYRK1A
SCHEMBL826881 0.83 PTPRC (0.62) PTPRCPTPN6PTPN11PTPN22EPHX2
SCHEMBL29379298 0.83 PTPRC (0.62) PTPRCPTPN6PTPN11PTPN22EPHX2
SCHEMBL15590663 0.81 PTPRC (0.44) PTPRCPTPN6PTPN11PTPN22MEN1
SCHEMBL3799533 0.79 ALDH1A1 (0.39) PTPRCPTPN6PTPN11PTPN22CYP2A6
SCHEMBL15582380 0.78 PTPRC (0.42) PTPRCPTPN6PTPN11PTPN22
SCHEMBL21025987 0.76 PTPRC (0.36) PTPRCPTPN6PTPN11PTPN22CYP2A6
SCHEMBL25572192 0.76 PTPRC (0.38) PTPRCPTPN6PTPN11PTPN22
SCHEMBL25571571 0.73 PTPRC (0.35) PTPRCPTPN6PTPN11PTPN22
SCHEMBL25572189 0.73 PTPRC (0.35) PTPRCPTPN6PTPN11PTPN22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116018039-B Tin-based perovskite material, and preparation method and application thereof 南方科技大学 2025-08-19 CN disclosed
US-20220213039-A1 PYRIDINIUM SALTS AND PEST CONTROL AGENT NIPPON SODA CO., LTD. (JP) 2022-07-07 US disclosed
CN-105263926-B Benzothienyl compounds 安斯泰来制药株式会社 2018-05-11 CN disclosed
EP-3006443-B1 BENZOTHIOPHENE COMPOUND ASTELLAS PHARMA INC (JP) 2018-04-25 EP disclosed
US-20170369486-A1 GEMINAL SUBSTITUTED QUINUCLIDINE AMIDE COMPOUNDS AS AGONISTS OF ALPHA-7 NICOTONIC ACETYLCHOLINE RECEPTORS AXOVANT SCIENCES GMBH (CH) 2017-12-28 US disclosed
CN-105503822-B The preparation method of trifluoromethyl benzothiophene derivative 温州大学 2017-11-24 CN disclosed
CN-104672220-B The activator of peroxisome proliferator-activated receptor 日本化学医药株式会社 2017-09-22 CN disclosed
CN-107074857-A Method for preparing crystallization organic semiconducting materials 巴斯夫欧洲公司 2017-08-18 CN disclosed
CN-107004768-A Organic semiconductor composition containing a liquid medium 巴斯夫欧洲公司 2017-08-01 CN disclosed
US-9399038-B2 Benzothiophene compound ASTELLAS PHARMA INC. (JP) 2016-07-26 US disclosed
US-20040220173-A1 Novel heterocyclic substituted carbonyl derivatives and their use as dopamine D3 receptor AVENTIS PHARMACEUTICAL INC. (US) 2004-11-04 US disclosed
EP-1392676-A2 HETEROCYCLIC UREA DERIVATIVES AND THEIR USE AS DOPAMINE D3 RECEPTOR LIGANDS Aventis Pharmaceuticals, Inc. (US) 2004-03-03 EP disclosed
US-20040030137-A1 Novel heterocyclic amide derivatives and their use as dopamine D3 receptor ligands AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2004-02-12 US disclosed
US-20030229066-A1 Novel heterocyclic urea derivatives and their use as dopamine D3 receptor ligands AVENTIS PHARMACEUTICALS INC. 2003-12-11 US disclosed
EP-1361875-A2 NOVEL HETEROCYCLIC AMIDE DERIVATIVES AND THEIR USE AS DOPAMINE D3 RECEPTOR LIGANDS Aventis Pharmaceuticals Inc. (US) 2003-11-19 EP disclosed
EP-1362039-A1 HETEROCYCLIC SUBSTITUTED CARBONYL DERIVATIVES AND THEIR USE AS DOPAMINE D3 RECEPTOR LIGANDS Aventis Pharmaceuticals, Inc. (US) 2003-11-19 EP disclosed
WO-2002066468-A2 HETEROCYCLIC UREA DERIVATIVES AND THEIR USE AS DOPAMINE D3 RECEPTOR LIGANDS AVENTIS PHARMACEUTICALS INC. (US) 2002-08-29 WO disclosed
WO-2002066469-A2 NOVEL HETEROCYCLIC AMIDE DERIVATIVES AND THEIR USE AS DOPAMINE D3 RECEPTOR LIGANDS AVENTIS PHARMACEUTICALS INC. (US) 2002-08-29 WO disclosed
WO-2002066446-A1 HETEROCYCLIC SUBSTITUTED CARBONYL DERIVATIVES AND THEIR USE AS DOPAMINE D3 RECEPTOR LIGANDS AVENTIS PHARMACEUTICALS INC. (US) 2002-08-29 WO disclosed
US-5304657-A Insecticides ISHIHARA SANGYO KAISHA LTD. (JP) 1994-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040030137-A1 Novel heterocyclic amide derivatives and their use as dopamine D3 receptor ligands DRD3, DRD2, DRD1 PTPRC 694/4885PTPN6 2453/4885PTPN11 2567/4885
US-20030229066-A1 Novel heterocyclic urea derivatives and their use as dopamine D3 receptor ligands DRD3, DRD2, DRD1 PTPRC 827/4885PTPN6 2603/4885PTPN11 2767/4885
US-20040220173-A1 Novel heterocyclic substituted carbonyl derivatives and their use as dopamine D3 receptor DRD3, DRD2, DRD1 PTPRC 368/4885PTPN6 2178/4885PTPN11 2305/4885
US-20170369486-A1 GEMINAL SUBSTITUTED QUINUCLIDINE AMIDE COMPOUNDS AS AGONISTS OF ALPHA-7 NICOTONIC ACETYLCHOLINE RECEPTORS CHRNA7, CHRNA6, CHRNA5 PTPRC 4307/4885PTPN6 3882/4885PTPN11 3855/4885
US-20220213039-A1 PYRIDINIUM SALTS AND PEST CONTROL AGENT ZYX, PNPO, PRDX1 PTPRC 808/4885PTPN6 64/4885PTPN11 212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.