SCHEMBL30278367

SCHEMBL30278367

COC(=O)C12CCC(C)(C)CC1C1=CCC3C4(C)CCC(=O)C(C)(C)C4CCC3(C)C1(C)CC2

nearest known ligand 0.81

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 6/20 0.81
▸ PTPN2 P17706 2/20 0.81
▸ F3 P13726 1/20 0.81
▸ PNLIP P16233 1/20 0.81
▸ NOS2 P35228 1/20 0.81
▸ CES2 O00748 2/20 0.72
▸ CES1 P23141 2/20 0.72
▸ NFE2L2 Q16236 3/20 0.65
▸ STAT3 P40763 1/20 0.64
▸ NFKB1 P19838 1/20 0.63
▸ NFKB2 Q00653 1/20 0.63
▸ RELA Q04206 1/20 0.63
▸ EGLN2 Q96KS0 1/20 0.63
▸ EGLN1 Q9GZT9 1/20 0.63
▸ EGLN3 Q9H6Z9 1/20 0.63
▸ P4HTM Q9NXG6 1/20 0.63
▸ PTGS2 P35354 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16152971 1.00 PTPN1 (0.81) PTPN1PTPN2F3PNLIPNOS2
SCHEMBL18687848 1.00 PTPN1 (0.81) PTPN1PTPN2F3PNLIPNOS2
Oleanonic Acid SCHEMBL18688313 0.89 PTPN2 (1.00) PTPN1PTPN2F3PNLIPNOS2
Oleanonic Acid SCHEMBL2762433 0.89 PTPN2 (1.00) PTPN1PTPN2F3PNLIPNOS2
Oleanonic Acid SCHEMBL12337276 0.89 PTPN2 (1.00) PTPN1PTPN2F3PNLIPNOS2
Oleanonic Acid SCHEMBL6898284 0.89 PTPN2 (1.00) PTPN1PTPN2F3PNLIPNOS2
SCHEMBL17166004 0.89 PTPN1 (0.85) PTPN1PTPN2F3PNLIPNOS2
Oleanonic Acid SCHEMBL18687844 0.89 PTPN2 (1.00) PTPN1PTPN2F3PNLIPNOS2
Oleanonic Acid SCHEMBL12200334 0.89 PTPN2 (1.00) PTPN1PTPN2F3PNLIPNOS2
Oleanonic Acid SCHEMBL12313105 0.89 PTPN2 (1.00) PTPN1PTPN2F3PNLIPNOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12507703-B2 Methods, devices and compositions for preserving human milk THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2025-12-30 — — US disclosed
US-20250169516-A1 METHODS, DEVICES AND COMPOSITIONS FOR PRESERVING HUMAN MILK THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2025-05-29 — — US disclosed
US-12239142-B2 Methods, devices and compositions for preserving human milk THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2025-03-04 — — US disclosed
US-20240376435-A1 KIDNEY ORGANOID AND METHOD FOR PRODUCING SAME OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2024-11-14 — — US disclosed
US-20240268402-A1 Methods, Devices and Compositions for Preserving Human Milk THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2024-08-15 — — US disclosed
EP-4397749-A1 KIDNEY ORGANOID AND METHOD FOR PRODUCING SAME Otsuka Pharmaceutical Co., Ltd. (JP) 2024-07-10 — — EP disclosed
WO-2023033137-A1 KIDNEY ORGANOID AND METHOD FOR PRODUCING SAME 大塚製薬株式会社 2023-03-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12507703-B2 Methods, devices and compositions for preserving human milk LPL, CEL, LPO PTPN1 4634/4885PTPN2 4668/4885F3 1704/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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