SCHEMBL16159059

SCHEMBL16159059

CCC(C)c1ccc2c(c1)sc1ccccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.47
MAPT P10636 4/20 0.47
HPGD P15428 3/20 0.47
RAB9A P51151 3/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
GPR3 P46089 1/20 0.47
ALOX15 P16050 2/20 0.40
USP2 O75604 1/20 0.40
GAA P10253 1/20 0.40
PKM P14618 1/20 0.40
HSD17B10 Q99714 1/20 0.40
MMP12 P39900 2/20 0.39
MMP13 P45452 2/20 0.39
HDAC4 P56524 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
L3MBTL1 Q9Y468 3/20 0.38
POLB P06746 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ATM Q13315 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25795387 1.00 ALDH1A1 (0.47) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL25795381 0.90 GPR3 (0.47) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL12386888 0.90 GPR3 (0.47) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL13338346 0.82 GPR3 (0.54) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL14665244 0.82 ALOX15 (0.46) ALDH1A1MAPTHPGDALOX15USP2
SCHEMBL11046600 0.81 KDM4E (0.53) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL8610327 0.79 ALDH1A1 (0.50) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL25721015 0.79 ALDH1A1 (0.50) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL23008021 0.78 MAPT (0.49) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL22591613 0.78 MAPT (0.49) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230212135-A1 LIGHT EMITTING ELEMENT, AMINE COMPOUND FOR THE SAME, AND DISPLAY DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-06 US disclosed
US-9773980-B2 Organic electroluminescent device KABUSHIKI KAISHA TOSHIBA (JP) 2017-09-26 US disclosed
US-20140299853-A1 ORGANIC ELECTROLUMINESCENT DEVICE KABUSHIKI KAISHA TOSHIBA (JP) 2014-10-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230212135-A1 LIGHT EMITTING ELEMENT, AMINE COMPOUND FOR THE SAME, AND DISPLAY DEVICE INCLUDING THE SAME SLC1A2, SLC18A2, SLC18A1 ALDH1A1 56/4885MAPT 767/4885HPGD 3554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.