Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GPR3 | P46089 | 1/20 | 0.50 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.47 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.37 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22000436 | 0.90 | UGT2B7 (0.44) | ALDH1A1MAPTRAB9AHPGDSMN1; SMN2 | |
| SCHEMBL13338346 | 0.85 | GPR3 (0.54) | ALDH1A1MAPTRAB9AHPGDSMN1; SMN2 | |
| SCHEMBL25721015 | 0.82 | ALDH1A1 (0.50) | ALDH1A1MAPTRAB9AHPGDSMN1; SMN2 | |
| SCHEMBL23008021 | 0.81 | MAPT (0.49) | ALDH1A1MAPTRAB9AHPGDSMN1; SMN2 | |
| SCHEMBL22591613 | 0.81 | MAPT (0.49) | ALDH1A1MAPTRAB9AHPGDSMN1; SMN2 | |
| SCHEMBL11248448 | 0.80 | AKR1B1 (0.55) | ALDH1A1MAPTRAB9AHPGDSMN1; SMN2 | |
| SCHEMBL25795387 | 0.79 | ALDH1A1 (0.47) | ALDH1A1MAPTRAB9AHPGDSMN1; SMN2 | |
| SCHEMBL16159059 | 0.79 | ALDH1A1 (0.47) | ALDH1A1MAPTRAB9AHPGDSMN1; SMN2 | |
| SCHEMBL21926352 | 0.78 | MAPT (0.58) | ALDH1A1MAPTRAB9AHPGDSMN1; SMN2 | |
| SCHEMBL2149947 | 0.76 | MAPT (0.50) | ALDH1A1MAPTRAB9AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807880-A | ANTICANCER AGENTS; DISEASES OF PROSTATE GLAND, MAMMARY GLANDS; ENDOMETRIOSIS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-09-15 | — | — | US | disclosed |
| CN-1131944-A | Azole derivative and pharmachutical composition thereof | YAMANOUCHI PHARMACUETICAL CO L (JP) | 1996-09-25 | — | — | CN | disclosed |
| EP-0721943-A1 | AZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-07-17 | — | — | EP | disclosed |