Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4358639 | 0.74 | L3MBTL1 (0.48) | ALDH1A1MAPTNPC1RAB9AHPGD | |
| SCHEMBL11556034 | 0.73 | MAPT (0.61) | ALDH1A1MAPTNPC1RAB9ANPSR1 | |
| SCHEMBL9672474 | 0.72 | MAPT (0.63) | ALDH1A1MAPTNPC1RAB9ANPSR1 | |
| SCHEMBL11385692 | 0.71 | ALDH1A1 (0.41) | ALDH1A1MAPTNPC1RAB9ALMNA | |
| SCHEMBL12369298 | 0.69 | ALDH1A1 (0.69) | ALDH1A1MAPTNPC1RAB9ANPSR1 | |
| SCHEMBL24127879 | 0.68 | ALDH1A1 (0.58) | ALDH1A1MAPTNPC1RAB9ANPSR1 | |
| SCHEMBL647938 | 0.68 | ALDH1A1 (0.70) | ALDH1A1NPC1RAB9AHPGDKDM4E | |
| SCHEMBL21156277 | 0.67 | DYRK1A (0.56) | — | |
| SCHEMBL24127872 | 0.67 | ALDH1A1 (0.56) | ALDH1A1MAPTNPC1RAB9ANPSR1 | |
| SCHEMBL21156826 | 0.67 | RAB9A (0.46) | ALDH1A1MAPTNPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9566224-B2 | Tyrosinase inhibitors | AVON PRODUCTS, INC. (US) | 2017-02-14 | — | — | US | disclosed |
| US-9566224-B2 | Tyrosinase inhibitors | AVON PRODUCTS, INC. (US) | 2017-02-14 | — | — | US | disclosed |
| US-20150174034-A1 | TYROSINASE INHIBITORS | AVON PRODUCTS, INC. | 2015-06-25 | — | — | US | disclosed |
| US-20150174034-A1 | TYROSINASE INHIBITORS | AVON PRODUCTS, INC. | 2015-06-25 | — | — | US | disclosed |
| US-20150118170-A1 | TYROSINASE INHIBITORS | AVON PRODUCTS, INC. | 2015-04-30 | — | — | US | disclosed |
| US-20150118170-A1 | TYROSINASE INHIBITORS | AVON PRODUCTS, INC. | 2015-04-30 | — | — | US | disclosed |
| WO-2014164200-A1 | TYROSINASE INHIBITORS | AVON PRODUCTS, INC (US) | 2014-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150174034-A1 | TYROSINASE INHIBITORS | TYR, CUTA, MAOA | ALDH1A1 541/4885MAPT 186/4885NPC1 2636/4885 |
| US-20150118170-A1 | TYROSINASE INHIBITORS | TYR, CUTA, MAOA | ALDH1A1 541/4885MAPT 186/4885NPC1 2636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.