Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1895593 | 0.98 | ALDH1A1 (0.30) | — | |
| Bromide SCHEMBL556685 | 0.93 | LMNA (0.35) | DNM1 | |
| SCHEMBL3835150 | 0.92 | OPRM1 (0.35) | — | |
| SCHEMBL16163417 | 0.91 | — | — | |
| SCHEMBL1245582 | 0.91 | LMNA (0.36) | DNM1 | |
| SCHEMBL1246523 | 0.91 | LMNA (0.36) | DNM1 | |
| Iodide SCHEMBL1475838 | 0.91 | OPRM1 (0.34) | — | |
| SCHEMBL1246152 | 0.91 | LMNA (0.36) | DNM1 | |
| SCHEMBL14973610 | 0.91 | LMNA (0.36) | DNM1 | |
| SCHEMBL1246124 | 0.91 | LMNA (0.36) | DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140305844-A1 | IONIC LIQUID FOR DESULFURIZATION OF LIGHT FUELS | KING ABDULAZIZ CITY FOR SCIENCE AND TECHNOLOGY (SA) | 2014-10-16 | — | — | US | disclosed |