Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.33 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 known ✓ | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.32 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.32 |
| ▸ | RAD52 | P43351 | 2/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1246523 | 0.98 | LMNA (0.36) | LMNADNM1OPRM1HTTSPHK1 | |
| SCHEMBL1246152 | 0.98 | LMNA (0.36) | LMNADNM1OPRM1HTTSPHK1 | |
| SCHEMBL1246124 | 0.98 | LMNA (0.36) | LMNADNM1OPRM1HTTSPHK1 | |
| SCHEMBL1245582 | 0.98 | LMNA (0.36) | LMNADNM1OPRM1HTTSPHK1 | |
| SCHEMBL14973610 | 0.98 | LMNA (0.36) | LMNADNM1OPRM1HTTSPHK1 | |
| SCHEMBL3835150 | 0.96 | OPRM1 (0.35) | LMNAOPRM1SPHK1CA1 | |
| Iodide SCHEMBL1475838 | 0.95 | OPRM1 (0.34) | LMNAOPRM1 | |
| Bromide SCHEMBL16163172 | 0.93 | DNM1 (0.31) | DNM1 | |
| SCHEMBL1895593 | 0.91 | ALDH1A1 (0.30) | — | |
| SCHEMBL5915818 | 0.85 | FFAR4 (0.39) | LMNAHSP90AA1HTTPLA2G1BATG4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10023968-B2 | Electric Al—Zr alloy plating bath using room temperature molten salt bath and plating method using the same | DIPSOL CHEMICALS CO., LTD. (JP) | 2018-07-17 | — | — | US | disclosed |
| US-20170241030-A9 | Electric Al-Zr-Mn Alloy-Plating Bath Using Room Temperature Molten Salt Bath, Plating Method Using the Same and Al-Zr-Mn Alloy-Plated Film | HONDA MOTOR CO., LTD. (JP) | 2017-08-24 | — | — | US | disclosed |
| EP-2130949-B1 | ELECTRIC Al-Zr ALLOY PLATING BATH USING ROOM TEMPERATURE MOLTEN SALT BATH AND PLATING METHOD USING THE SAME | DIPSOL CHEM (JP) | 2016-08-31 | — | — | EP | disclosed |
| US-20150159290-A1 | Electric Al-Zr-Mn Alloy-Plating Bath Using Room Temperature Molten Salt Bath, Plating Method Using the Same and Al-Zr-Mn Alloy-Plated Film | HONDA MOTOR CO., LTD. (JP) | 2015-06-11 | — | — | US | disclosed |
| US-8821707-B2 | Electric Al or Al alloy plating bath using room temperature molten salt bath and plating method using the same | DIPSOL CHEMICALS CO., LTD. (JP) | 2014-09-02 | — | — | US | disclosed |
| US-20120052324-A1 | Electric Al-Zr-Mn Alloy-Plating Bath Using Room Temperature Molten Salt Bath, Plating Method Using the Same and Al-Zr-Mn Alloy-Plated Film | HONDA MOTOR CO., LTD. (JP) | 2012-03-01 | — | — | US | disclosed |
| US-20120031766-A1 | Electric Al or Al Alloy Plating Bath Using Room Temperature Molten Salt Bath and Plating Method Using the Same | HONDA MOTOR CO., LTD. (JP) | 2012-02-09 | — | — | US | disclosed |
| US-20100285322-A1 | Electric Al-Zr Alloy Plating Bath Using Room Temperature Molten Salt Bath and Plating Method Using the Same | DIPSOL CHEMICALS CO., LTD. (JP) | 2010-11-11 | — | — | US | disclosed |
| EP-2130949-A1 | ELECTRIC Al-Zr ALLOY PLATING BATH USING ROOM TEMPERATURE MOLTEN SALT BATH AND PLATING METHOD USING THE SAME | Dipsol Chemicals Co., Ltd. (JP) | 2009-12-09 | — | — | EP | disclosed |