Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | ADH4 | P08319 | 1/20 | 0.32 |
| ▸ | ADH7 | P40394 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1245582 | 1.00 | LMNA (0.36) | LMNAOPRM1SPHK1CYP2D6ADH1B | |
| SCHEMBL14973610 | 1.00 | LMNA (0.36) | LMNAOPRM1SPHK1CYP2D6ADH1B | |
| SCHEMBL1246152 | 1.00 | LMNA (0.36) | LMNAOPRM1SPHK1CYP2D6ADH1B | |
| SCHEMBL1246124 | 1.00 | LMNA (0.36) | LMNAOPRM1SPHK1CYP2D6ADH1B | |
| Bromide SCHEMBL556685 | 0.98 | LMNA (0.35) | LMNAOPRM1SPHK1CYP2D6ADH1B | |
| Bromide SCHEMBL28428048 | 0.98 | LMNA (0.35) | LMNAOPRM1SPHK1CYP2D6ADH1B | |
| SCHEMBL3835150 | 0.98 | OPRM1 (0.35) | LMNAOPRM1SPHK1 | |
| Iodide SCHEMBL1475838 | 0.96 | OPRM1 (0.34) | LMNAOPRM1 | |
| SCHEMBL1895593 | 0.92 | ALDH1A1 (0.30) | — | |
| Bromide SCHEMBL16163172 | 0.91 | DNM1 (0.31) | DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8991179-B2 | Drive unit and method for its operation | STEAMDRIVE GMBH (DE) | 2015-03-31 | — | — | US | disclosed |
| US-20110023483-A1 | Drive unit and method for its operation | VOITH PATENT GMBH (DE) | 2011-02-03 | — | — | US | disclosed |