SCHEMBL161641

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL161011	0.91	ALDH1A1 (0.44)	F10KMT2AALDH1A1CASP1CASP7
	SCHEMBL167620	0.81	ALDH1A1 (0.42)	F10KMT2AALDH1A1CASP1CASP7
	SCHEMBL161435	0.81	ALDH1A1 (0.42)	F10KMT2AALDH1A1CASP1CASP7
	SCHEMBL113651	0.81	CXCR3 (0.51)	F10KMT2AALDH1A1CASP1CASP7
	SCHEMBL112005	0.79	GRAMD1A (0.53)	F10KMT2AALDH1A1CASP1CASP7
	SCHEMBL112189	0.78	F10 (0.44)	F10KMT2AALDH1A1CASP1CASP7
	SCHEMBL3105176	0.78	RAB9A (0.43)	ALDH1A1CASP1CASP7USP2HSD17B10
	SCHEMBL160558	0.73	RAB9A (0.42)	KMT2AALDH1A1HSD17B10RAB9AMAPT
	SCHEMBL112526	0.73	F10 (0.47)	F10KMT2AALDH1A1CASP1CASP7
	SCHEMBL13077265	0.73	ROCK2 (0.43)	F10KMT2AALDH1A1CASP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.