Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20303765 | 0.78 | XPO1 (0.33) | — | |
| SCHEMBL7627026 | 0.77 | SIRT2 (0.32) | — | |
| SCHEMBL3869526 | 0.77 | CTSL (0.32) | CTSLCTSSCTSK | |
| SCHEMBL15228583 | 0.75 | SLC40A1 (0.31) | — | |
| SCHEMBL29705395 | 0.74 | TRPV3 (0.31) | TRPV3 | |
| SCHEMBL13082570 | 0.74 | DHFR (0.36) | TRPV3 | |
| SCHEMBL22721535 | 0.74 | KDM4E (0.36) | TRPV3 | |
| SCHEMBL15243578 | 0.74 | TRPV3 (0.31) | TRPV3 | |
| SCHEMBL25310060 | 0.73 | PDCD1LG2 (0.33) | — | |
| SCHEMBL15321296 | 0.72 | ALDH1A1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2984086-A1 | BACE1 INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2016-02-17 | — | — | EP | disclosed |
| WO-2014166906-A1 | BACE1 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2014-10-16 | — | — | WO | disclosed |