Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.45 |
| ▸ | BAD | Q92934 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30777455 | 0.79 | BCL2L1 (0.45) | BCL2L1BADALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1616679 | 0.79 | BCL2L1 (0.45) | BCL2L1BADALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9136887 | 0.75 | BCL2L1 (0.50) | BCL2L1BADALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL1044992 | 0.75 | BCL2L1 (0.50) | BCL2L1BADALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL19249411 | 0.73 | BCL2L1 (0.48) | BCL2L1BADALDH1A1SMN1; SMN2TSHR | |
| Dimethylamine SCHEMBL6542151 | 0.73 | BCL2L1 (0.44) | BCL2L1BADALDH1A1TSHRLMNA | |
| SCHEMBL413550 | 0.73 | BCL2L1 (0.52) | BCL2L1BADALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL29892288 | 0.73 | BCL2L1 (0.52) | BCL2L1BADALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL31462459 | 0.72 | BCL2L1 (0.33) | BCL2L1BADNPSR1 | |
| SCHEMBL10651162 | 0.72 | BCL2L1 (0.47) | BCL2L1BADALDH1A1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 415 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239805-A1 | AZA-YANG CYCLIZATION-BUCHNER AROMATIC RING EXPANSION: COLLECTIVE SYNTHESIS OF CYCLOHEPTATRIENE-CONTAINING AZETIDINE LACTONES | UNIVERSITY OF KANSAS | 2024-07-18 | — | — | US | disclosed |
| EP-4398911-A2 | INK4 TUMOR SUPPRESSOR PROTEINS MEDIATE RESISTANCE TO CDK4/6 KINASE INHIBITORS | Memorial Sloan Kettering Cancer Center (US) | 2024-07-17 | — | — | EP | disclosed |
| US-12037414-B2 | Processes for preparing pharmaceutically relevant peptides | STEALTH BIOTHERAPEUTICS INC. (US) | 2024-07-16 | — | — | US | disclosed |
| US-12024515-B2 | Kifunensine derivatives | UNIVERSITY OF KANSAS (US) | 2024-07-02 | — | — | US | disclosed |
| EP-4384524-A1 | DERIVATIVES OF TURBINMICIN AS ANTIFUNGAL AGENTS | Wisconsin Alumni Research Foundation (US) | 2024-06-19 | — | — | EP | disclosed |
| WO-2024123818-A1 | FUNCTIONALIZED COLLOIDAL SILICA AND METHODS OF PRODUCTION | W.R. GRACE & CO.-CONN (US) | 2024-06-13 | — | — | WO | disclosed |
| EP-4370701-A1 | TEXTILES DERIVED FROM FOOD WASTE AND PROCESSES OF MAKING THEREOF | Alt Tex Inc. (CA) | 2024-05-22 | — | — | EP | disclosed |
| WO-2024102441-A1 | PROCESSING AID FORMULATION AND POLYOLEFIN FILMS MADE THEREFROM | Amcor Flexibles North America, Inc. (US) | 2024-05-16 | — | — | WO | disclosed |
| WO-2024097229-A1 | PROBENECID COMPOUNDS FOR THE TREATMENT OF INFLAMMASOME-MEDIATED DERMATOLOGICAL CONDITIONS | BACAINN BIOTHERAPEUTICS, INC. (US) | 2024-05-10 | — | — | WO | disclosed |
| WO-2024097945-A1 | PRODRUGS FOR MITOCHONDRIAL CALCIUM UPTAKE INHIBITORS | CORNELL UNIVERSITY (US) | 2024-05-10 | — | — | WO | disclosed |
| US-20110009628-A1 | Compounds and Compositions for Modulating Lipid Levels and Methods of Preparing Same | CVI PHARMACEUTICALS LIMITED (KY) | 2011-01-13 | — | — | US | disclosed |
| WO-2011006000-A1 | BERBERINE DERIVATIVES USEFUL FOR MODULATING LIPID LEVELS AND THEIR METHODS OF SYNTHESIS | LIU HAIYAN (US) | 2011-01-13 | — | — | WO | disclosed |
| WO-2010143062-A1 | COMPOSITIONS AND METHODS FOR PREVENTION AND TREATMENT OF CORONARY HEART DISEASES | GENEREX PHARMACEUTICALS, INC. (CN) | 2010-12-16 | — | — | WO | disclosed |
| US-20100261871-A1 | CONFORMATIONALLY CONSTRAINED PEPTIDE MIMETICS | INDIAN INSTITUTE OF SCIENCE | 2010-10-14 | — | — | US | disclosed |
| US-20100228004-A1 | TEMPLATES FOR NUCLEATION AND PROPAGATION OF PEPTIDE SECONDARY STRUCTURE | EMPIRE TECHNOLOGY DEVELOPMENT LLC | 2010-09-09 | — | — | US | disclosed |
| US-20100048637-A1 | CYCLOHEXYLAMINES, PHENYLAMINES AND USES THEREOF | PEKING UNIVERSITY SHENZHEN GRADUATE SCHOOL (CN) | 2010-02-25 | — | — | US | disclosed |
| WO-2010014948-A1 | METHODS OF TREATMENT USING WNT INHIBITORS | THE UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2010-02-04 | — | — | WO | disclosed |
| US-20100016638-A1 | Method for preparation of o-desmethylvenlafaxine using polythiolates | PLIVA HRVATSKA D.O.O (HR) | 2010-01-21 | — | — | US | disclosed |
| US-20090048246-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR REDUCING LIPID LEVELS | CVI PHARMACEUTICALS LIMITED (KY) | 2009-02-19 | — | — | US | disclosed |
| WO-2009002873-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR REDUCING LIPID LEVELS | CVI PHARMACEUTICALS LIMITED (KY) | 2008-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239805-A1 | AZA-YANG CYCLIZATION-BUCHNER AROMATIC RING EXPANSION: COLLECTIVE SYNTHESIS OF CYCLOHEPTATRIENE-CONTAINING AZETIDINE LACTONES | AZI2, NISCH, TET2 | BCL2L1 2299/4885BAD 230/4885ALDH1A1 1283/4885 |
| US-20110009628-A1 | Compounds and Compositions for Modulating Lipid Levels and Methods of Preparing Same | LIPC, LDLR, PCSK9 | BCL2L1 1983/4885BAD 2706/4885ALDH1A1 3512/4885 |
| US-20100016638-A1 | Method for preparation of o-desmethylvenlafaxine using polythiolates | CYP4F3, CYP2F1, CYP4F2 | BCL2L1 4024/4885BAD 4166/4885ALDH1A1 1755/4885 |
| US-20100228004-A1 | TEMPLATES FOR NUCLEATION AND PROPAGATION OF PEPTIDE SECONDARY STRUCTURE | IAPP, NGLY1, HDGF | BCL2L1 2537/4885BAD 3601/4885ALDH1A1 4099/4885 |
| US-20100048637-A1 | CYCLOHEXYLAMINES, PHENYLAMINES AND USES THEREOF | SMO, HNMT, INMT | BCL2L1 2596/4885BAD 1131/4885ALDH1A1 915/4885 |
| US-12037414-B2 | Processes for preparing pharmaceutically relevant peptides | ADM2, VIP, PEPD | BCL2L1 4695/4885BAD 4212/4885ALDH1A1 4638/4885 |
| US-20100261871-A1 | CONFORMATIONALLY CONSTRAINED PEPTIDE MIMETICS | IAPP, VIP, HM13 | BCL2L1 1037/4885BAD 611/4885ALDH1A1 4832/4885 |
| US-20090048246-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR REDUCING LIPID LEVELS | LIPC, BCHE, LIPE | BCL2L1 3358/4885BAD 1189/4885ALDH1A1 4483/4885 |
| US-12024515-B2 | Kifunensine derivatives | MAN2B1, MAN2A1, MANBA | BCL2L1 3080/4885BAD 3228/4885ALDH1A1 1479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.