Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 6/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.39 |
| ▸ | RARB | P10826 | 4/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | CSF3R | Q99062 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | ATP4A | P20648 | 1/20 | 0.36 |
| ▸ | ATP4B | P51164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16169754 | 0.93 | PDK2 (0.38) | PDK2CSF3RRXRARXRBRXRG | |
| SCHEMBL16419745 | 0.86 | CYP2D6 (0.42) | CYP2D6CYP3A4CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL16169683 | 0.83 | PLA2G2A (0.43) | CYP2D6CYP3A4CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL15274996 | 0.83 | RXRA (0.40) | CYP2D6CYP3A4CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL16169676 | 0.83 | RXRA (0.40) | CYP2D6CYP3A4CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL16419735 | 0.81 | CYP2D6 (0.45) | CYP2D6CYP3A4CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL16169744 | 0.81 | RXRA (0.39) | CYP19A1CYP2C9CYP2C19CYP1A2KDM4E | |
| SCHEMBL16419742 | 0.80 | LTA4H (0.49) | CYP2D6CYP3A4CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL16419790 | 0.80 | HRH3 (0.39) | KDM4ENPC1RAB9ACSF3R | |
| SCHEMBL16169670 | 0.79 | CYP1A2 (0.38) | CYP2D6CYP3A4CYP19A1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140308317-A1 | Polymeric Compounds And Methods Of Making And Using The Same | CELLCEUTIX CORPORATION (US) | 2014-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140308317-A1 | Polymeric Compounds And Methods Of Making And Using The Same | ALG1, CD44, MUC1 | CYP2D6 3113/4885CYP3A4 3480/4885CYP19A1 4661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.